Discuss This Drug

betrixaban

CHEBI:CHEBI_140421

Definition

A secondary carboxamide obtained by formal condensation of the carboxy group of 4-(N,N-dimethylcarbamimidoyl)benzoic acid with the amino group of 2-amino-N-(5-chloropyridin-2-yl)-5-methoxybenzamide. A synthetic anticoagulant compound that targets activated factor Xa in the coagulation cascade.

Chemical Information

Molecular Formula
C23H22ClN5O3
Molecular Mass
451.906
Charge
0
SMILES
C1(=CC=C(C=C1)C(NC2=CC=C(C=C2C(=O)NC=3C=CC(=CN3)Cl)OC)=O)C(N(C)C)=N
InChI
InChI=1S/C23H22ClN5O3/c1-29(2)21(25)14-4-6-15(7-5-14)22(30)27-19-10-9-17(32-3)12-18(19)23(31)28-20-11-8-16(24)13-26-20/h4-13,25H,1-3H3,(H,27,30)(H,26,28,31)
InChIKey
XHOLNRLADUSQLD-UHFFFAOYSA-N

Alternative Names

  • betrixaban
  • N-(5-chloropyridin-2-yl)-2-[4-(N,N-dimethylcarbamimidoyl)benzamido]-5-methoxybenzamide
  • PRT 054021
  • PRT054021

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
1927851
oboInOwl#hasDbXref
Reaxys:15486817
core#notation
CHEBI:140421

Additional References

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
1927851
oboInOwl#hasDbXref
Reaxys:15486817
oboInOwl#id
CHEBI:140421
core#notation
CHEBI:140421
listing_expiration_date
20241231
dosage_form
POWDER
marketing_start_date
20200228
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
active_ingredient_strength
1 kg/kg
package_marketing_start_date
28-FEB-20
labeler_name
MSN Life Sciences Private Limited
generic_name
Betrixaban Maleate
product_ndc
69766-087
spl_id
0c3b870e-7b49-c200-e063-6394a90a547b
active_ingredient_name
BETRIXABAN MALEATE
package_ndc
69766-087-01
package_description
50 kg in 1 DRUM (69766-087-01)
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_68581
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect5201
owl#annotatedSource
t108866
owl#someValuesFrom
t3174095