Cisatracurium
CHEBI:CHEBI_140621
Definition
A diester that is the (1R,1'R,2R,2'R)-diastereoisomer of atracurium, a quaternary ammonium ion consisting of pentane-1,5-diol with both hydroxy functions bearing 3-[1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-3,4-dihydroisoquinolinium-2(1H)-yl]propanoyl groups. The active species in the skeletal muscle relaxant cisatracurium besylate.
Chemical Information
- Molecular Formula
- C53H72N2O12
- Molecular Mass
- 929.147
- Charge
- +2
- SMILES
- C=12[C@H]([N@+](CCC1C=C(OC)C(=C2)OC)(CCC(OCCCCCOC(CC[N@@+]3([C@@H](C4=C(C=C(OC)C(=C4)OC)CC3)CC5=CC(=C(OC)C=C5)OC)C)=O)=O)C)CC6=CC(=C(OC)C=C6)OC
- InChI
- InChI=1S/C53H72N2O12/c1-54(22-18-38-32-48(62-7)50(64-9)34-40(38)42(54)28-36-14-16-44(58-3)46(30-36)60-5)24-20-52(56)66-26-12-11-13-27-67-53(57)21-25-55(2)23-19-39-33-49(63-8)51(65-10)35-41(39)43(55)29-37-15-17-45(59-4)47(31-37)61-6/h14-17,30-35,42-43H,11-13,18-29H2,1-10H3/q+2/t42-,43-,54-,55-/m1/s1
- InChIKey
- YXSLJKQTIDHPOT-LJCJQEJUSA-N
Alternative Names
- (1R-cis,1'R-cis)-2,2'-{pentane-1,5-diylbis[oxy(3-oxopropane-3,1-diyl)]}bis[1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolinium]
- (1R-cis,1'R-cis)-atracurium
- (1R,2R,1'R,2'R)-2,2'-{pentane-1,5-diylbis[oxy(3-oxopropane-3,1-diyl)]}bis[1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolinium]
- (1R,2R,1'R,2'R)-atracurium
Drug Classification
-
quaternary ammonium ionView Class →
CHEBI:35267
-
diesterView Class →
CHEBI:51307
-
t108343
-
t108573
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 319864
- oboInOwl#hasDbXref
- Reaxys:8184048
- core#notation
- CHEBI:140621
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- package_marketing_start_date
- 17-NOV-11
- package_description
- 2 kg in 1 BAG (58175-0541-0)
- package_ndc
- 70069-141-01
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 319864
- oboInOwl#hasDbXref
- Reaxys:8184048
- oboInOwl#id
- CHEBI:140621
- brand_name
- Cisatracurium besylate
- brand_name_base
- Cisatracurium besylate
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT
- dosage_form
- INJECTION, SOLUTION
- generic_name
- Cisatracurium besylate
- product_ndc
- 58175-0541
- application_number
- ANDA213527
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_48878
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- core#notation
- CHEBI:140621
- rxcui
- 1730194
- manufacturer_name
- PIRAMAL CRITICAL CARE INC
- active_ingredient_strength
- 2 kg/2kg
- pharm_class
- Nondepolarizing Neuromuscular Blocker [EPC]
- active_ingredient_name
- CISATRACURIUM BESYLATE
- unii
- 80YS8O1MBS
- spl_set_id
- 91130e22-e30e-49c1-9633-96b469585e74
- upc
- 0307813152705
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- owl#annotatedSource
- t108907
- owl#someValuesFrom
- t2909773
- listing_expiration_date
- 20241231
- marketing_start_date
- 20171207
- labeler_name
- PIRAMAL CRITICAL CARE INC
- route
- INTRAVENOUS
- spl_id
- 1f8326e8-8619-08b8-e063-6394a90a0af1