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tyloxapol

CHEBI:CHEBI_141517

Definition

A polymeric compound resulting from the reaction of 4-(1,1,3,3-tetramethylbutyl)phenol with formaldehyde to give a chain in which 6-8 molecules are linked together by CH2 groups ortho to the phenolic hydroxy groups, which have then undergone reaction with oxirane to give polyoxyethyleneoxy moieties, Ar(OCH2CH2)xOH, where x = 8-10. A nonionic liquic polymer, it inhibits lipoprotein lipase and hence clearance of triglyceride from the plasma, so is used to induce hyperlipidaemia in test animals. Also used as a surfactant to aid liquefaction and removal of mucus- and pus-containing bronchopulmonary secretions.

Chemical Information

Molecular Formula
(C2H4O)n.(C2H4O)n.(C17H26O2)n.(C2H4O)n.C29H44O2
Charge
0

Alternative Names

  • 4-(1,1,2,2-tetramethylbutyl)phenol polyer with formaldehyde and oxirane
  • Alevaire
  • oxyethylated tertiary octylphenol formaldehyde polymer
  • p-(1,1,3,3-tetramethylbutyl)phenol polymer with ethylene oxide and formaldehyde
  • p-isooctylpolyoxyethylenenphenol formaldehyde polymer
  • Superinone
  • tiloxapol
  • Triton A-20
  • Triton WR-1339
  • tyloxapol
  • tyloxapolum
  • tyloxypal

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
38998
oboInOwl#hasDbXref
Wikipedia:Tyloxapol
core#notation
CHEBI:141517

Additional References

Wikipedia:Tyloxapol

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Additional Attributes

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chebi_ontology
DRON_00010000
38998
oboInOwl#hasDbXref
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core#notation
CHEBI:141517
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_75324
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect5239
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t108870
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t1529291