Discuss This Drug

estetrol

CHEBI:CHEBI_142773

Definition

A 3-hydroxy steroid that is 17beta-estradiol which has been substituted at the 15alpha and 16alpha positions by two additional hydroxy groups. It is a natural estrogen produced exclusively during pregnancy by the fetal liver.

Chemical Information

Molecular Formula
C18H24O4
Molecular Mass
304.381
Charge
0
SMILES
C12=CC=C(C=C1CC[C@@]3([C@@]2(CC[C@]4([C@]3([C@H]([C@H]([C@@H]4O)O)O)[H])C)[H])[H])O
InChI
InChI=1S/C18H24O4/c1-18-7-6-12-11-5-3-10(19)8-9(11)2-4-13(12)14(18)15(20)16(21)17(18)22/h3,5,8,12-17,19-22H,2,4,6-7H2,1H3/t12-,13-,14-,15-,16-,17+,18+/m1/s1
InChIKey
AJIPIJNNOJSSQC-NYLIRDPKSA-N

Alternative Names

  • (15alpha,16alpha,17beta)-estra-1(10),2,4-triene-3,15,16,17-tetrol
  • (8R,9S,13S,14S,15R,16R,17R)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,15,16,17-tetrol
  • 15alpha-hydroxyestriol
  • 3,15alpha,16alpha,17beta-tetrahydroxyestra-1,3,5(10)-triene
  • Donesta
  • estetrol
  • estetrolum
  • estra-1,3,5(10)-triene-3,15alpha,16alpha,17beta-tetrol
  • estra-1(10),2,4-triene-3,15alpha,16alpha,17beta-tetrol
  • oestetrol

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
2539031
oboInOwl#hasDbXref
Wikipedia:Estetrol
core#notation
CHEBI:142773

Additional References

Wikipedia:Estetrol

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
2539031
oboInOwl#hasDbXref
Wikipedia:Estetrol
oboInOwl#id
CHEBI:142773
core#notation
CHEBI:142773
listing_expiration_date
20251231
dosage_form
POWDER
marketing_start_date
20191115
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
active_ingredient_strength
1 kg/kg
labeler_name
PCAS
package_marketing_start_date
15-NOV-19
generic_name
Estetrol Monohydrate
product_ndc
10577-918
spl_id
f19c88f5-ac5b-a234-e053-2a95a90acf87
active_ingredient_name
ESTETROL
package_ndc
10577-918-10
package_description
20 kg in 1 DRUM (10577-918-10)
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50114
chebi#has_parent_hydride
http://purl.obolibrary.org/obo/CHEBI_23966
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_108568
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect5303
owl#annotatedSource
t112555
owl#someValuesFrom
t3776580