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Trospium

CHEBI:CHEBI_145791

Definition

A carboxylic ester resulting from the formal condensation of the carboxy group of hydroxy(diphenyl)acetic acid with the hydroxy group of (1S,3R,5R)-3-hydroxy-8lambda(5)-azaspiro[bicyclo[3.2.1]octane-8,1'-pyrrolidin]-8-ylium. Its chloride salt is used to treat overactive bladder.

Chemical Information

Molecular Formula
C25H30NO3
Molecular Mass
392.518
Charge
+1
SMILES
[N+]12([C@]3(C[C@H](OC(C(C4=CC=CC=C4)(C5=CC=CC=C5)O)=O)C[C@@]1(CC3)[H])[H])CCCC2
InChI
InChI=1S/C25H30NO3/c27-24(25(28,19-9-3-1-4-10-19)20-11-5-2-6-12-20)29-23-17-21-13-14-22(18-23)26(21)15-7-8-16-26/h1-6,9-12,21-23,28H,7-8,13-18H2/q+1/t21-,22+,23+
InChIKey
OYYDSUSKLWTMMQ-JKHIJQBDSA-N

Alternative Names

  • (1alpha,3beta,5alpha)-3-[(2-hydroxy-2,2-diphenylacetyl)oxy]-spiro[8-azoniabicyclo[3.2.1]octane-8,1'-pyrrolidinium]
  • (1S,3R,5R)-3-[(2-hydroxy-2,2-diphenylacetyl)oxy]-8lambda(5)-azaspiro[bicyclo[3.2.1]octane-8,1'-pyrrolidin]-8-ylium
  • tropsium cation
  • tropsium ion

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:145791
DRON_00010000
236778
oboInOwl#hasDbXref
PMID:31602966

Additional References

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

rxcui
857564
manufacturer_name
35573
package_marketing_start_date
20221203
package_description
30 CAPSULE in 1 BOTTLE (35573-446-30)
unii
1E6682427E
spl_set_id
97c9cc28-7635-4ecd-9855-6982cc396c52
package_ndc
90096-141-60
core#notation
CHEBI:145791
active_ingredient_strength
50 kg/50kg
pharm_class
Cholinergic Muscarinic Antagonists [MoA]
brand_name_suffix
ER
active_ingredient_name
TROSPIUM CHLORIDE
upc
0390096141603
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
236778
oboInOwl#hasDbXref
PMID:31602966
oboInOwl#id
CHEBI:145791
product_type
BULK INGREDIENT
dosage_form
CAPSULE, EXTENDED RELEASE
marketing_category
EXPORT ONLY
labeler_name
35573
generic_name
TROSPIUM CHLORIDE ER
brand_name
TROSPIUM CHLORIDE ER
brand_name_base
TROSPIUM CHLORIDE ER
product_ndc
35573-446
application_number
ANDA215781
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_53784
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
listing_expiration_date
20241231
route
ORAL
marketing_start_date
20221203
spl_id
f389cc21-71b1-c110-e053-2a95a90a933b
has_treatment
http://purl.obolibrary.org/obo/DOID_0080174
owl#annotatedSource
t112553
owl#someValuesFrom
t2884180