dehydroemetine
CHEBI:CHEBI_149634
Definition
A pyridoisoquinoline which was developed in response to the cardiovascular toxicity associated with emetine and results from the dehydrogenation of the heterotricylic ring of emetine. It is an antiprotozoal agent and displays antimalarial, antiamoebic, and antileishmanial properties.
Chemical Information
- Molecular Formula
- C29H38N2O4
- Molecular Mass
- 478.633
- Charge
- 0
- SMILES
- [C@H]1(C2=C(C=C(OC)C(=C2)OC)CCN1)CC=3C[C@]4(C=5C=C(OC)C(OC)=CC5CCN4CC3CC)[H]
- InChI
- InChI=1S/C29H38N2O4/c1-6-18-17-31-10-8-20-14-27(33-3)29(35-5)16-23(20)25(31)12-21(18)11-24-22-15-28(34-4)26(32-2)13-19(22)7-9-30-24/h13-16,24-25,30H,6-12,17H2,1-5H3/t24-,25+/m1/s1
- InChIKey
- XXLZPUYGHQWHRN-RPBOFIJWSA-N
Alternative Names
- (-)-2,3-dehydroemetine
- (-)-R,S-dehydroemetine
- 2-dehydroemetine
- 2,3-didehydro-6',7',10,11-tetramethoxyemetan
- 2,3-didehydroemetine
- 6',7',10,11-tetramethoxy-2,3-didehydroemetan
- BT 436
- Dametin
- dehidroemetina
- dehydroemetine
- dehydroemetinum
- Mebadin
- Mebadine
- Ro 1-9334
- Ro 1-9334/19
- Ro-1-9334/19
- Ro-1933419
Treatment Applications
-
obsolete Chagas cardiomyopathyView Disease →
DOID:12569
Drug Classification
-
processed material
-
isoquinolinesView Class →
CHEBI:24922
-
aromatic etherView Class →
CHEBI:35618
-
pyridoisoquinolineView Class →
CHEBI:61692
-
t112157
-
t112241
-
t112518
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 3142
- oboInOwl#hasDbXref
- Wikipedia:Dehydroemetine
- core#notation
- CHEBI:149634
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 3142
- oboInOwl#hasDbXref
- Wikipedia:Dehydroemetine
- oboInOwl#id
- CHEBI:149634
- core#notation
- CHEBI:149634
- oboInOwl#hasAlternativeId
- CHEBI:4363
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_38068
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- chebi#has_parent_hydride
- http://purl.obolibrary.org/obo/CHEBI_36380
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_108122
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect5486
- owl#annotatedSource
- t116086
- owl#someValuesFrom
- t481361