lumefantrine
CHEBI:CHEBI_156095
Definition
A member of the class of fluorenes that is 9-(p-chlorobenzylidene)-9H-fluorene which is substitutec by chlorine at positions 2 and 7, and by a 2-(dibutylamino)-1-hydroxyethyl group at position 4. An antimalarial drug used in combination with artemether for the treatment of multi-drug resistant strains of falciparum malaria.
Chemical Information
- Molecular Formula
- C30H32Cl3NO
- Molecular Mass
- 528.94000
- Charge
- 0
- SMILES
- CCCCN(CCCC)CC(O)c1cc(Cl)cc2\C(=C/c3ccc(Cl)cc3)c3cc(Cl)ccc3-c12
- InChI
- InChI=1S/C30H32Cl3NO/c1-3-5-13-34(14-6-4-2)19-29(35)28-18-23(33)17-27-25(15-20-7-9-21(31)10-8-20)26-16-22(32)11-12-24(26)30(27)28/h7-12,15-18,29,35H,3-6,13-14,19H2,1-2H3/b25-15-
- InChIKey
- DYLGFOYVTXJFJP-MYYYXRDXSA-N
Alternative Names
- (+-)-2,7-Dichloro-9-((Z)-p-chlorobenzylidene)-alpha-((dibutylamino)methyl)fluorene-4-methanol
- 2-(dibutylamino)-1-[(9Z)-2,7-dichloro-9-(4-chlorobenzylidene)-9H-fluoren-4-yl]ethanol
- 2-Dibutylamino-1-[2,7-dichloro-9-(4-chloro-benzylidene)-9H-fluoren-4-yl]-ethanol
- 2-Dibutylamino-1-{2,7-dichloro-9-[1-(4-chloro-phenyl)-meth-(Z)-ylidene]-9H-fluoren-4-yl}-ethanol
- Benflumetol
- dl-Benflumelol
- Lumefantrine
Drug Classification
-
tertiary amineView Class →
CHEBI:32876
-
secondary alcoholView Class →
CHEBI:35681
-
monochlorobenzenesView Class →
CHEBI:83403
-
fluorenesView Class →
CHEBI:24059
-
t115491
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 847728
- oboInOwl#hasDbXref
- Wikipedia:Lumefantrine
- core#notation
- CHEBI:156095
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 847728
- oboInOwl#hasDbXref
- Wikipedia:Lumefantrine
- oboInOwl#id
- CHEBI:156095
- core#notation
- CHEBI:156095
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_38068
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect7100
- owl#annotatedSource
- t116096
- owl#someValuesFrom
- t1009498