Discuss This Drug

lumefantrine

CHEBI:CHEBI_156095

Definition

A member of the class of fluorenes that is 9-(p-chlorobenzylidene)-9H-fluorene which is substitutec by chlorine at positions 2 and 7, and by a 2-(dibutylamino)-1-hydroxyethyl group at position 4. An antimalarial drug used in combination with artemether for the treatment of multi-drug resistant strains of falciparum malaria.

Chemical Information

Molecular Formula
C30H32Cl3NO
Molecular Mass
528.94000
Charge
0
SMILES
CCCCN(CCCC)CC(O)c1cc(Cl)cc2\C(=C/c3ccc(Cl)cc3)c3cc(Cl)ccc3-c12
InChI
InChI=1S/C30H32Cl3NO/c1-3-5-13-34(14-6-4-2)19-29(35)28-18-23(33)17-27-25(15-20-7-9-21(31)10-8-20)26-16-22(32)11-12-24(26)30(27)28/h7-12,15-18,29,35H,3-6,13-14,19H2,1-2H3/b25-15-
InChIKey
DYLGFOYVTXJFJP-MYYYXRDXSA-N

Alternative Names

  • (+-)-2,7-Dichloro-9-((Z)-p-chlorobenzylidene)-alpha-((dibutylamino)methyl)fluorene-4-methanol
  • 2-(dibutylamino)-1-[(9Z)-2,7-dichloro-9-(4-chlorobenzylidene)-9H-fluoren-4-yl]ethanol
  • 2-Dibutylamino-1-[2,7-dichloro-9-(4-chloro-benzylidene)-9H-fluoren-4-yl]-ethanol
  • 2-Dibutylamino-1-{2,7-dichloro-9-[1-(4-chloro-phenyl)-meth-(Z)-ylidene]-9H-fluoren-4-yl}-ethanol
  • Benflumetol
  • dl-Benflumelol
  • Lumefantrine

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
847728
oboInOwl#hasDbXref
Wikipedia:Lumefantrine
core#notation
CHEBI:156095

Additional References

Wikipedia:Lumefantrine

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
847728
oboInOwl#hasDbXref
Wikipedia:Lumefantrine
oboInOwl#id
CHEBI:156095
core#notation
CHEBI:156095
listing_expiration_date
20251231
dosage_form
POWDER
marketing_start_date
20130116
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
active_ingredient_strength
1 kg/kg
labeler_name
Zhejiang Medicine Co., Ltd. Xinchang Pharmaceutical Factory
package_marketing_start_date
16-JAN-13
generic_name
LUMEFANTRINE
active_ingredient_name
LUMEFANTRINE
product_ndc
67254-909
spl_id
229a19e6-170e-4943-8b7d-e59cdef9b2b8
package_ndc
67254-909-01
package_description
60 kg in 1 DRUM (67254-909-01)
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_38068
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect7100
owl#annotatedSource
t116096
owl#someValuesFrom
t1009498