Aztreonam
CHEBI:CHEBI_161680
Definition
A synthetic monocyclic beta-lactam antibiotic (monobactam), used primarily to treat infections caused by Gram-negative bacteria. It inhibits mucopeptide synthesis in the bacterial cell wall, thereby blocking peptidoglycan crosslinking.
Chemical Information
- Molecular Formula
- C13H17N5O8S2
- Molecular Mass
- 435.43300
- Charge
- 0
- SMILES
- C[C@H]1[C@H](NC(=O)C(=N/OC(C)(C)C(O)=O)\c2csc([NH3+])n2)C(=O)N1S([O-])(=O)=O
- InChI
- InChI=1S/C13H17N5O8S2/c1-5-7(10(20)18(5)28(23,24)25)16-9(19)8(6-4-27-12(14)15-6)17-26-13(2,3)11(21)22/h4-5,7H,1-3H3,(H2,14,15)(H,16,19)(H,21,22)(H,23,24,25)/b17-8-/t5-,7-/m0/s1
- InChIKey
- WZPBZJONDBGPKJ-VEHQQRBSSA-N
Alternative Names
- AZT
- (2S,3S)-3-{(2Z)-2-(2-ammonio-1,3-thiazol-4-yl)-2-[(2-carboxypropan-2-yloxy)imino]acetamido}-2-methyl-4-oxoazetidine-1-sulfonate
- (Z,)-2-((((2-Amino-4-thiazolyl)(((2S,3S,)-2-methyl-4-oxo-1-sulfo-3-azetidinyl)carbamoyl)methylene)amino)oxy)-2-methylpropionic acid
- Azactam
- aztreonam
- aztreonamum
- Primbactam
Drug Classification
-
beta-lactam antibiotic allergenView Class →
CHEBI:88225
-
monobactamView Class →
CHEBI:50695
-
t122211
-
t122720
-
t123250
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- oboInOwl#hasDbXref
- Wikipedia:Aztreonam
- DRON_00010000
- 1272
- core#notation
- CHEBI:161680
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- rxcui
- 1664988
- listing_expiration_date
- 20241231
- route
- INTRAVENOUS
- marketing_start_date
- 20171121
- package_marketing_start_date
- 26-MAY-17
- manufacturer_name
- Gilead Sciences, Inc.
- spl_id
- 1596bbb0-748c-7adf-e063-6294a90a6cdc
- package_ndc
- 61126-710-01
- package_description
- 1 BAG in 1 DRUM (61126-710-01) / 1 BAG in 1 BAG (61126-710-02) / 1 kg in 1 BAG
- unii
- G2B4VE5GH8
- spl_set_id
- c6cf7e13-a04e-47e2-9cec-44a278ee6bec
- oboInOwl#hasOBONamespace
- chebi_ontology
- oboInOwl#hasDbXref
- Wikipedia:Aztreonam
- DRON_00010000
- 1272
- generic_name
- Aztreonam Anhydrous
- brand_name
- AZACTAM
- brand_name_base
- AZACTAM
- prefixIRI
- CHEBI:161680
- oboInOwl#id
- CHEBI:161680
- oboInOwl#hasAlternativeId
- CHEBI:41008
- dosage_form
- INHALANT
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
- labeler_name
- Latina Pharma S.p.A.
- product_ndc
- 61126-710
- application_number
- NDA050580
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_50696
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- core#notation
- CHEBI:161680
- active_ingredient_strength
- 200 kg/200kg
- active_ingredient_name
- AZTREONAM
- nui
- M0014030
- pharm_class_epc
- Monobactam Antibacterial [EPC]
- pharm_class
- Monobactams [CS]
- pharm_class_cs
- Monobactams [CS]
- upc
- 0363323402013
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- RO_0001022
- http://purl.obolibrary.org/obo/DOID_0040037
- has_treatment
- http://purl.obolibrary.org/obo/DOID_1485
- owl#annotatedSource
- t123396
- owl#someValuesFrom
- t3364201