Discuss This Drug

monomethyl fumarate

CHEBI:CHEBI_167450

Definition

A dicarboxylic acid monoester resulting from the formal condensation of one of the carboxy groups of fumaric acid with methanol. Is is a metabolite of dimethyl fumarate and used for the the treatment of patients with relapsing multiple sclerosis (MS). It also induces the NFE2L2 (Nrf2) transcription factor by binding to KEAP1.

Chemical Information

Molecular Formula
C5H6O4
Molecular Mass
130.099
Charge
0
SMILES
COC(=O)\C=C\C(O)=O
InChI
InChI=1S/C5H6O4/c1-9-5(8)3-2-4(6)7/h2-3H,1H3,(H,6,7)/b3-2+
InChIKey
NKHAVTQWNUWKEO-NSCUHMNNSA-N

Alternative Names

  • (2E)-4-methoxy-4-oxobut-2-enoic acid
  • (E)-4-methoxy-4-oxobut-2-enoic acid
  • Bafiertam
  • fumarate de monomethyle
  • fumarato de monometilo
  • fumaric acid monomethyl ester
  • methyl hydrogen fumarate
  • MMF
  • mono-methyl fumarate
  • monomethyl fumarate
  • monomethylfumarate
  • monomethylis fumaras

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:167450
DRON_00010000
1546433
oboInOwl#hasDbXref
Wikipedia:Monomethyl_fumarate

Additional References

Wikipedia:Monomethyl_fumarate

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:167450
active_ingredient_strength
1 kg/kg
package_marketing_start_date
28-APR-20
active_ingredient_name
MONOMETHYL FUMARATE
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
1546433
oboInOwl#hasDbXref
Wikipedia:Monomethyl_fumarate
oboInOwl#id
CHEBI:167450
generic_name
Monomethyl Fumarate
listing_expiration_date
20241231
dosage_form
CAPSULE
marketing_start_date
20161231
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
labeler_name
MSN Life Sciences Private Limited
product_ndc
44657-0082
spl_id
e16888ee-1549-e486-e053-2a95a90a3c20
package_ndc
44657-0082-0
package_description
1 kg in 1 DRUM (44657-0082-0)
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_49103
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_18012
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect8045
owl#annotatedSource
t127030
owl#someValuesFrom
t3866557