Mycophenolic Acid

CHEBI:CHEBI_168396

Definition

A member of the class of 2-benzofurans that is 2-benzofuran-1(3H)-one which is substituted at positions 4, 5, 6, and 7 by methyl, methoxy, (2E)-5-carboxy-3-methylpent-2-en-1-yl, and hydroxy groups, respectively. It is an antibiotic produced by Penicillium brevi-compactum, P. stoloniferum, P. echinulatum and related species. An immunosuppressant, it is widely used (partiularly as its sodium salt and as the 2-(morpholin-4-yl)ethyl ester prodrug, mycophenolate mofetil) to prevent tissue rejection following organ transplants and for the treatment of certain autoimmune diseases.

Chemical Information

Molecular Formula
C17H20O6
Molecular Mass
320.33710
Charge
0
SMILES
COc1c(C)c2COC(=O)c2c(O)c1C\C=C(/C)CCC(O)=O
InChI
InChI=1S/C17H20O6/c1-9(5-7-13(18)19)4-6-11-15(20)14-12(8-23-17(14)21)10(2)16(11)22-3/h4,20H,5-8H2,1-3H3,(H,18,19)/b9-4+
InChIKey
HPNSFSBZBAHARI-RUDMXATFSA-N

Alternative Names

  • (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoic acid
  • (E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid
  • acide mycophenolique
  • acido micofenolico
  • acidum mycophenolicum
  • Micofenolico acido
  • Mycophenolate
  • mycophenolic acid
  • Mycophenolsaeure

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
7145
oboInOwl#hasDbXref
Wikipedia:Mycophenolic_acid
core#notation
CHEBI:168396

Additional References

Wikipedia:Mycophenolic_acid

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

package_marketing_start_date
20040227
package_description
100 BLISTER PACK in 1 CARTON (0904-6785-61) / 1 TABLET, DELAYED RELEASE in 1 BLISTER PACK
package_ndc
68084-918-25
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
7145
oboInOwl#hasDbXref
Wikipedia:Mycophenolic_acid
oboInOwl#id
CHEBI:168396
oboInOwl#hasAlternativeId
CHEBI:43973
generic_name
MYCOPHENOLIC ACID
brand_name
Myfortic
brand_name_base
Myfortic
dosage_form
TABLET, DELAYED RELEASE
product_ndc
0904-6785
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_76964
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_62932
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_8764
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
listing_expiration_date
20241231
route
ORAL
marketing_start_date
20040227
labeler_name
airis PHARMA Private Limited
application_number
ANDA218603
spl_id
63d2921c-ee9a-4dc5-a9e7-8e6428d2d239
core#notation
CHEBI:168396
rxcui
616450
pharm_class
Antimetabolite Immunosuppressant [EPC]
active_ingredient_strength
360 mg/1
manufacturer_name
airis PHARMA Private Limited
active_ingredient_name
MYCOPHENOLIC ACID
unii
WX877SQI1G
spl_set_id
5b224d7f-fecb-4531-9d27-008347777c9d
upc
0370377040115
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_0080649
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_62932
owl#annotatedSource
t127047
owl#someValuesFrom
t3001653