Discuss This Drug

Cortisone

CHEBI:CHEBI_16962

Definition

A C21-steroid that is pregn-4-ene substituted by hydroxy groups at positions 17 and 21 and oxo group at positions 3, 11 and 20.

Chemical Information

Molecular Formula
C21H28O5
Molecular Mass
360.44402
Charge
0
SMILES
[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])C(=O)C[C@@]1(C)[C@@]2([H])CC[C@]1(O)C(=O)CO
InChI
InChI=1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-15,18,22,26H,3-8,10-11H2,1-2H3/t14-,15-,18+,19-,20-,21-/m0/s1
InChIKey
MFYSYFVPBJMHGN-ZPOLXVRWSA-N

Alternative Names

  • 11-dehydro-17-hydroxycorticosterone
  • 17-hydroxy-11-dehydrocorticosterone
  • 17,21-dihydroxypregn-4-ene-3,11,20-trione
  • 17alpha,21-dihydroxy-4-pregnene-3,11,20-trione
  • 17alpha,21-Dihydroxy-4-pregnene-3,11,20-trione
  • 4-pregnene-17alpha,21-diol-3,11,20-trione
  • Cortison
  • cortisone
  • Cortisone
  • Delta(4)-pregnene-17alpha,21-diol-3,11,20-trione
  • Kendall's compound E
  • Kortison
  • pregn-4-en-17alpha,21-diol-3,11,20-trione
  • Reichstein's substance Fa
  • Wintersteiner's compound F

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
2878
oboInOwl#hasDbXref
Wikipedia:Cortisone
core#notation
CHEBI:16962

Additional References

Wikipedia:Cortisone

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

has_treatment
http://purl.obolibrary.org/obo/DOID_1586
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
2878
oboInOwl#hasDbXref
Wikipedia:Cortisone
oboInOwl#hasAlternativeId
CHEBI:3896
oboInOwl#id
CHEBI:16962
listing_expiration_date
20241231
route
ORAL
dosage_form
PELLET
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
marketing_start_date
20180911
package_marketing_start_date
08-AUG-22
labeler_name
Boiron
manufacturer_name
Boiron
generic_name
Cortisone Aceticum, Adrenalinum, Chininum Arsenicosum, Helonias Dioica, Hypericum Perforatum, Kali Phosphoricum, Nux Vomica, Selenium Metallicum, Aurum Metallicum, Bacillus 7 (Enterobacter Cloacae)
brand_name
Bio Mood Phase
brand_name_base
Bio Mood Phase
product_ndc
43742-1258
spl_id
d75fc007-3071-4114-9cb5-4aa4686778a3
package_ndc
43742-1258-1
package_description
30 mL in 1 BOTTLE, DROPPER (43742-1258-1)
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_77746
chebi#has_parent_hydride
http://purl.obolibrary.org/obo/CHEBI_8386
BFO_0000053
http://purl.obolibrary.org/obo/DRON_00000060
active_ingredient_name
ENTEROBACTER CLOACAE
core#notation
CHEBI:16962
pharm_class
Seed Storage Proteins [CS]
nui
M0516536
pharm_class_epc
Non-Standardized Plant Allergenic Extract [EPC]
pharm_class_pe
Increased IgG Production [PE]
pharm_class_cs
Seed Storage Proteins [CS]
pharm_class_moa
Adrenergic beta-Agonists [MoA]
unii
40OMQ8YEPD
active_ingredient_strength
30 [hp_C]/30[hp_C]
spl_set_id
81d6e6db-94dc-4b6f-9ef7-9180ec54eebf
upc
0810151881713
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect8357
owl#annotatedSource
t130682
owl#someValuesFrom
t1001424