Discuss This Drug

Cortisone

CHEBI:CHEBI_16962

Definition

A C21-steroid that is pregn-4-ene substituted by hydroxy groups at positions 17 and 21 and oxo group at positions 3, 11 and 20.

Chemical Information

Molecular Formula
C21H28O5
Molecular Mass
360.44402
Charge
0
SMILES
[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])C(=O)C[C@@]1(C)[C@@]2([H])CC[C@]1(O)C(=O)CO
InChI
InChI=1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-15,18,22,26H,3-8,10-11H2,1-2H3/t14-,15-,18+,19-,20-,21-/m0/s1
InChIKey
MFYSYFVPBJMHGN-ZPOLXVRWSA-N

Alternative Names

  • 11-dehydro-17-hydroxycorticosterone
  • 17-hydroxy-11-dehydrocorticosterone
  • 17,21-dihydroxypregn-4-ene-3,11,20-trione
  • 17alpha,21-dihydroxy-4-pregnene-3,11,20-trione
  • 17alpha,21-Dihydroxy-4-pregnene-3,11,20-trione
  • 4-pregnene-17alpha,21-diol-3,11,20-trione
  • Cortison
  • cortisone
  • Cortisone
  • Delta(4)-pregnene-17alpha,21-diol-3,11,20-trione
  • Kendall's compound E
  • Kortison
  • pregn-4-en-17alpha,21-diol-3,11,20-trione
  • Reichstein's substance Fa
  • Wintersteiner's compound F

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
2878
oboInOwl#hasDbXref
Wikipedia:Cortisone
core#notation
CHEBI:16962

Additional References

Wikipedia:Cortisone

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

has_treatment
http://purl.obolibrary.org/obo/DOID_1586
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
2878
oboInOwl#hasDbXref
Wikipedia:Cortisone
oboInOwl#hasAlternativeId
CHEBI:3896
oboInOwl#id
CHEBI:16962
core#notation
CHEBI:16962
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_77746
chebi#has_parent_hydride
http://purl.obolibrary.org/obo/CHEBI_8386
BFO_0000053
http://purl.obolibrary.org/obo/DRON_00000060
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect8357
owl#annotatedSource
t130682
owl#someValuesFrom
t1001424