Discuss This Drug

Calcitriol

CHEBI:CHEBI_17823

Definition

A hydroxycalciol that is calcidiol in which the pro-S hydrogen of calcidiol is replaced by a hydroxy group. It is the active form of vitamin D3, produced fom calciol via hydoxylation in the liver to form calcidiol, which is subsequently oxidised in the kidney to give calcitriol.

Chemical Information

Molecular Formula
C27H44O3
Molecular Mass
416.63646
Charge
0
SMILES
[H][C@@]1(CC[C@@]2([H])\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C)[C@H](C)CCCC(C)(C)O
InChI
InChI=1S/C27H44O3/c1-18(8-6-14-26(3,4)30)23-12-13-24-20(9-7-15-27(23,24)5)10-11-21-16-22(28)17-25(29)19(21)2/h10-11,18,22-25,28-30H,2,6-9,12-17H2,1,3-5H3/b20-10+,21-11-/t18-,22-,23-,24+,25+,27-/m1/s1
InChIKey
GMRQFYUYWCNGIN-NKMMMXOESA-N

Alternative Names

  • (1alpha,3beta,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol
  • (1S,3R,5Z,7E)-9,10-secocholesta-5,7,10-triene-1,3,25-triol
  • (1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol
  • (5Z,7E)-(1S,3R)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol
  • 1-alpha-25-Dihydroxyvitamin D3
  • 1,25-DHCC
  • 1alpha,25-dihydroxycholecalciferol
  • 1alpha,25-dihydroxyvitamin D3
  • 1alpha,25(OH)2D3
  • 5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL
  • Calcijex
  • calcitriol
  • calcitriol
  • Calcitriol
  • calcitriolum
  • Decostriol
  • Rocaltrol

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
1894
oboInOwl#hasDbXref
Wikipedia:Calcitriol
core#notation
CHEBI:17823

Additional References

Wikipedia:Calcitriol

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
1894
oboInOwl#hasDbXref
Wikipedia:Calcitriol
oboInOwl#hasAlternativeId
CHEBI:46435
oboInOwl#id
CHEBI:17823
core#notation
CHEBI:17823
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_38807
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_13543
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect10415
owl#annotatedSource
t137927
owl#someValuesFrom
t2987489