Discuss This Drug

Calcitriol

CHEBI:CHEBI_17823

Definition

A hydroxycalciol that is calcidiol in which the pro-S hydrogen of calcidiol is replaced by a hydroxy group. It is the active form of vitamin D3, produced fom calciol via hydoxylation in the liver to form calcidiol, which is subsequently oxidised in the kidney to give calcitriol.

Chemical Information

Molecular Formula
C27H44O3
Molecular Mass
416.63646
Charge
0
SMILES
[H][C@@]1(CC[C@@]2([H])\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C)[C@H](C)CCCC(C)(C)O
InChI
InChI=1S/C27H44O3/c1-18(8-6-14-26(3,4)30)23-12-13-24-20(9-7-15-27(23,24)5)10-11-21-16-22(28)17-25(29)19(21)2/h10-11,18,22-25,28-30H,2,6-9,12-17H2,1,3-5H3/b20-10+,21-11-/t18-,22-,23-,24+,25+,27-/m1/s1
InChIKey
GMRQFYUYWCNGIN-NKMMMXOESA-N

Alternative Names

  • (1alpha,3beta,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol
  • (1S,3R,5Z,7E)-9,10-secocholesta-5,7,10-triene-1,3,25-triol
  • (1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol
  • (5Z,7E)-(1S,3R)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol
  • 1-alpha-25-Dihydroxyvitamin D3
  • 1,25-DHCC
  • 1alpha,25-dihydroxycholecalciferol
  • 1alpha,25-dihydroxyvitamin D3
  • 1alpha,25(OH)2D3
  • 5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL
  • Calcijex
  • calcitriol
  • calcitriol
  • Calcitriol
  • calcitriolum
  • Decostriol
  • Rocaltrol

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
1894
oboInOwl#hasDbXref
Wikipedia:Calcitriol
core#notation
CHEBI:17823

Additional References

Wikipedia:Calcitriol

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

listing_expiration_date
20241231
route
INTRAVENOUS
spl_id
2eef31a6-f775-43b5-bd03-f35ef5840821
package_ndc
71335-1594-4
marketing_start_date
20161227
package_marketing_start_date
21-NOV-05
manufacturer_name
FOSUN PHARMA USA INC
package_description
30 CAPSULE, LIQUID FILLED in 1 BOTTLE, PLASTIC (63629-2445-1)
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
dosage_form
CAPSULE, GELATIN COATED
labeler_name
MicroBiopharm Japan Co., Ltd
application_number
ANDA209798
product_ndc
66499-0003
rxcui
261283
active_ingredient_name
CALCITRIOL
active_ingredient_strength
1.6 g/1.6g
unii
FXC9231JVH
spl_set_id
7e0574e0-3a41-486a-be37-92ab56b7f81f
nui
N0000175908
pharm_class_epc
Vitamin D3 Analog [EPC]
pharm_class
Cholecalciferol [CS]
pharm_class_cs
Cholecalciferol [CS]
upc
0300540007133
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
1894
oboInOwl#hasDbXref
Wikipedia:Calcitriol
generic_name
Calcitriol Capsules 0.5 mcg
brand_name
Calcitrol
brand_name_base
Calcitrol
oboInOwl#hasAlternativeId
CHEBI:46435
oboInOwl#id
CHEBI:17823
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_38807
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
core#notation
CHEBI:17823
has_treatment
http://purl.obolibrary.org/obo/DOID_13543
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect10415
owl#annotatedSource
t137927
owl#someValuesFrom
t2987489