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N(4)-hydroxycytidine

CHEBI:CHEBI_180654

Definition

A nucleoside analogue that is cytidine which carries a hydroxy group at the N(4)-positon. It has broad-spectrum antiviral activity against influenza, SARS-CoV , SARS-CoV-2 and MERS-CoV.

Chemical Information

Molecular Formula
C9H13N3O6
Molecular Mass
259.218
Charge
0
SMILES
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=CC(NC1=O)=NO
InChI
InChI=1S/C9H13N3O6/c13-3-4-6(14)7(15)8(18-4)12-2-1-5(11-17)10-9(12)16/h1-2,4,6-8,13-15,17H,3H2,(H,10,11,16)/t4-,6-,7-,8-/m1/s1
InChIKey
XCUAIINAJCDIPM-XVFCMESISA-N

Alternative Names

  • 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-4-(hydroxyimino)-3,4-dihydropyrimidin-2(1H)-one
  • 4-N-hydroxycytidine
  • 4-oxime uridine
  • beta-D-N(4)-hydroxycytidine
  • EIDD 1931
  • EIDD-1931
  • N-hydroxy-3,4-dihydrocytidine
  • N-hydroxycytidine
  • N(4)-hydroxycytidine
  • NHC

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
PMID:34509661
core#notation
CHEBI:180654

Additional References

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Additional Attributes

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http://purl.obolibrary.org/obo/CHEBI_17562
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core#notation
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RO_0000087
http://purl.obolibrary.org/obo/CHEBI_49103
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http://purl.obolibrary.org/obo/chebi#3_STAR
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