Discuss This Drug

Triiodothyronine

CHEBI:CHEBI_18258

Definition

An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Chemical Information

Molecular Formula
C15H12I3NO4
Molecular Mass
650.97350
Charge
0
SMILES
N[C@@H](Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1)C(O)=O
InChI
InChI=1S/C15H12I3NO4/c16-9-6-8(1-2-13(9)20)23-14-10(17)3-7(4-11(14)18)5-12(19)15(21)22/h1-4,6,12,20H,5,19H2,(H,21,22)/t12-/m0/s1
InChIKey
AUYYCJSJGJYCDS-LBPRGKRZSA-N

Alternative Names

  • 3,3',5-triiodo-L-thyronine
  • 3,5,3'-Triiodo-L-thyronine
  • 3,5,3'-Triiodothyronine
  • 3,5,3'TRIIODOTHYRONINE
  • 4-(4-hydroxy-3-iodophenoxy)-3,5-diiodo-L-phenylalanine
  • L-3,5,3'-Triiodothyronine
  • L-T3
  • liothyronine
  • Liothyronine
  • liothyroninum
  • liotironina
  • O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine
  • T3
  • Tertroxin
  • Tresitope
  • Triiodothyronine

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
10814
oboInOwl#hasDbXref
Wikipedia:Triiodothyronine
core#notation
CHEBI:18258

Additional References

Wikipedia:Triiodothyronine

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
10814
oboInOwl#hasDbXref
Wikipedia:Triiodothyronine
oboInOwl#hasAlternativeId
CHEBI:9722
oboInOwl#id
CHEBI:18258
core#notation
CHEBI:18258
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_77746
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#is_tautomer_of
http://purl.obolibrary.org/obo/CHEBI_533015
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_60308
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_111321
has_treatment
http://purl.obolibrary.org/obo/DOID_11634
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_60308
owl#annotatedSource
t141566
owl#someValuesFrom
t3103180