Methoxsalen
CHEBI:CHEBI_18358
Definition
A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.
Chemical Information
- Molecular Formula
- C12H8O4
- Molecular Mass
- 216.18950
- Charge
- 0
- SMILES
- COc1c2occc2cc2ccc(=O)oc12
- InChI
- InChI=1S/C12H8O4/c1-14-12-10-8(4-5-15-10)6-7-2-3-9(13)16-11(7)12/h2-6H,1H3
- InChIKey
- QXKHYNVANLEOEG-UHFFFAOYSA-N
Alternative Names
- 6-hydroxy-7-methoxy-5-benzofuranacrylic acid delta-lactone
- 8-methoxy-[furano-3'.2':6.7-coumarin]
- 8-methoxy-2',3',6,7-furocoumarin
- 8-methoxy-4',5':6,7-furocoumarin
- 8-Methoxyfuranocoumarin
- 8-methoxypsoralen
- 8-Methoxypsoralen
- 8-MOP
- 8-MP
- 9-methoxy-7H-furo[3,2-g][1]benzopyran-7-one
- 9-methoxy-7H-furo[3,2-g]chromen-7-one
- Meladinine
- Meloxine
- Methoxsalen
- METHOXSALEN
- O-methylxanthotoxol
- O-Methylxanthotoxol
- Oxsoralen
- Ultra Mop
- Uvadex
- xanthotoxin
- Xanthotoxin
Drug Classification
-
aromatic etherView Class →
CHEBI:35618
-
psoralensView Class →
CHEBI:26369
-
t144062
-
t144265
-
t144626
-
t145105
-
t145258
-
t145302
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- oboInOwl#hasDbXref
- Wikipedia:Methoxsalen
- DRON_00010000
- 6854
- core#notation
- CHEBI:18358
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- oboInOwl#hasDbXref
- Wikipedia:Methoxsalen
- DRON_00010000
- 6854
- oboInOwl#hasAlternativeId
- CHEBI:40342
- oboInOwl#id
- CHEBI:18358
- generic_name
- METHOXSALEN
- brand_name
- UVADEX
- brand_name_base
- UVADEX
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT
- listing_expiration_date
- 20241231
- route
- EXTRACORPOREAL
- dosage_form
- CAPSULE, LIQUID FILLED
- labeler_name
- Therakos LLC
- marketing_start_date
- 19990225
- product_ndc
- 64067-216
- spl_id
- f0f6f409-ef35-4f7d-84d5-e5d521cea7ef
- application_number
- NDA020969
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_50684
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- chebi#has_functional_parent
- http://purl.obolibrary.org/obo/CHEBI_27616
- core#notation
- CHEBI:18358
- active_ingredient_name
- METHOXSALEN
- rxcui
- 1812434
- active_ingredient_strength
- 20 ug/mL
- package_marketing_start_date
- 19990225
- manufacturer_name
- Therakos LLC
- pharm_class_moa
- Photoabsorption [MoA]
- pharm_class
- Psoralens [CS]
- pharm_class_epc
- Psoralen [EPC]
- pharm_class_pe
- Photosensitizing Activity [PE]
- package_ndc
- 64067-216-01
- package_description
- 12 VIAL, GLASS in 1 CARTON (64067-216-01) / 10 mL in 1 VIAL, GLASS
- unii
- U4VJ29L7BQ
- spl_set_id
- 5ad333bd-845f-43f8-9ecf-43491f26c7c7
- nui
- M0017973
- pharm_class_cs
- Psoralens [CS]
- upc
- 0364067216010
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect10680
- owl#annotatedSource
- t145255
- owl#someValuesFrom
- t749270