Methoxsalen

CHEBI:CHEBI_18358

Definition

A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.

Chemical Information

Molecular Formula
C12H8O4
Molecular Mass
216.18950
Charge
0
SMILES
COc1c2occc2cc2ccc(=O)oc12
InChI
InChI=1S/C12H8O4/c1-14-12-10-8(4-5-15-10)6-7-2-3-9(13)16-11(7)12/h2-6H,1H3
InChIKey
QXKHYNVANLEOEG-UHFFFAOYSA-N

Alternative Names

  • 6-hydroxy-7-methoxy-5-benzofuranacrylic acid delta-lactone
  • 8-methoxy-[furano-3'.2':6.7-coumarin]
  • 8-methoxy-2',3',6,7-furocoumarin
  • 8-methoxy-4',5':6,7-furocoumarin
  • 8-Methoxyfuranocoumarin
  • 8-methoxypsoralen
  • 8-Methoxypsoralen
  • 8-MOP
  • 8-MP
  • 9-methoxy-7H-furo[3,2-g][1]benzopyran-7-one
  • 9-methoxy-7H-furo[3,2-g]chromen-7-one
  • Meladinine
  • Meloxine
  • Methoxsalen
  • METHOXSALEN
  • O-methylxanthotoxol
  • O-Methylxanthotoxol
  • Oxsoralen
  • Ultra Mop
  • Uvadex
  • xanthotoxin
  • Xanthotoxin

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Methoxsalen
DRON_00010000
6854
core#notation
CHEBI:18358

Additional References

Wikipedia:Methoxsalen

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Methoxsalen
DRON_00010000
6854
oboInOwl#hasAlternativeId
CHEBI:40342
oboInOwl#id
CHEBI:18358
generic_name
METHOXSALEN
brand_name
UVADEX
brand_name_base
UVADEX
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
listing_expiration_date
20241231
route
EXTRACORPOREAL
dosage_form
CAPSULE, LIQUID FILLED
labeler_name
Therakos LLC
marketing_start_date
19990225
product_ndc
64067-216
spl_id
f0f6f409-ef35-4f7d-84d5-e5d521cea7ef
application_number
NDA020969
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50684
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_27616
core#notation
CHEBI:18358
active_ingredient_name
METHOXSALEN
rxcui
1812434
active_ingredient_strength
20 ug/mL
package_marketing_start_date
19990225
manufacturer_name
Therakos LLC
pharm_class_moa
Photoabsorption [MoA]
pharm_class
Psoralens [CS]
pharm_class_epc
Psoralen [EPC]
pharm_class_pe
Photosensitizing Activity [PE]
package_ndc
64067-216-01
package_description
12 VIAL, GLASS in 1 CARTON (64067-216-01) / 10 mL in 1 VIAL, GLASS
unii
U4VJ29L7BQ
spl_set_id
5ad333bd-845f-43f8-9ecf-43491f26c7c7
nui
M0017973
pharm_class_cs
Psoralens [CS]
upc
0364067216010
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect10680
owl#annotatedSource
t145255
owl#someValuesFrom
t749270