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Desonide

CHEBI:CHEBI_204734

Definition

Triamcinolone acetonide with hydrogen instead of the fluorine substituent at position 9. A corticosteroid anti-inflammatory, it is used topically as a cream, ointment or lotion for the treatment of various skin disorders.

Chemical Information

Molecular Formula
C24H32O6
Molecular Mass
416.50730
Charge
0
SMILES
[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]1(C)[C@@]2([H])C[C@H]2OC(C)(C)O[C@@]12C(=O)CO
InChI
InChI=1S/C24H32O6/c1-21(2)29-19-10-16-15-6-5-13-9-14(26)7-8-22(13,3)20(15)17(27)11-23(16,4)24(19,30-21)18(28)12-25/h7-9,15-17,19-20,25,27H,5-6,10-12H2,1-4H3/t15-,16-,17-,19+,20+,22-,23-,24+/m0/s1
InChIKey
WBGKWQHBNHJJPZ-LECWWXJVSA-N

Alternative Names

  • (4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-5-hydroxy-6b-(hydroxyacetyl)-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
  • 11beta,21-dihydroxy-16alpha,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
  • 11beta,21-dihydroxy-16alpha,17-isopropylidenedioxypregna-1,4-diene-3,20-dione
  • 11beta,21-dihydroxy-16alpha,17alpha-isopropylidenedioxypregna-1,4-diene-3,20-dione
  • 16alpha-hydroxyprednisole-16,17-acetonide
  • 16alpha-hydroxyprednisolone-16alpha,17-acetonide
  • 16alpha,17alpha-isopropylidenedioxyprednisolone
  • desfluorotriamcinolone acetonide
  • desonida
  • desonide
  • desonidum

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:204734
DRON_00010000
3254
oboInOwl#hasDbXref
Wikipedia:Desonide

Additional References

Wikipedia:Desonide

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:204734
pharm_class_moa
Corticosteroid Hormone Receptor Agonists [MoA]
pharm_class
Corticosteroid [EPC]
pharm_class_epc
Corticosteroid [EPC]
nui
N0000175450
active_ingredient_name
DESONIDE
active_ingredient_strength
.03 g/60g
upc
0362332632152
spl_set_id
9eade7ae-effc-49b5-af7d-8caa183ff252
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
3254
oboInOwl#hasDbXref
Wikipedia:Desonide
oboInOwl#id
CHEBI:204734
generic_name
DESONIDE MICRONIZED
brand_name
Desonide Ointment, 0.05%
brand_name_base
Desonide Ointment, 0.05%
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
dosage_form
LOTION
product_ndc
38779-3043
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35472
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
listing_expiration_date
20241231
labeler_name
Hubei Gedian Humanwell Pharmaceutical Co., Ltd.
marketing_start_date
20010312
application_number
ANDA214396
spl_id
1ab36e2d-ff3a-53e5-e063-6394a90a0ff2
route
TOPICAL
package_ndc
38779-3043-6
package_description
1 g in 1 BOTTLE (38779-3043-6)
rxcui
205534
manufacturer_name
Encore Dermatology Inc
package_marketing_start_date
23-MAR-17
unii
J280872D1O
has_treatment
http://purl.obolibrary.org/obo/DOID_8741
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_109579
owl#annotatedSource
t145177
owl#someValuesFrom
t626714