Discuss This Drug

Clobetasol

CHEBI:CHEBI_205919

Definition

A 3-oxo-Delta(1),Delta(4)-steroid that is 16beta-methylpregna-1,4-diene-3,20-dione bearing hydroxy groups at the 11beta and 17alpha positions, fluorine at position 9, and a chlorine substituent at position 21. It is used as its 17alpha-propionate ester to treat various skin disorders, including exzema and psoriasis.

Chemical Information

Molecular Formula
C22H28ClFO4
Molecular Mass
410.90700
Charge
0
SMILES
[H][C@@]12C[C@H](C)[C@](O)(C(=O)CCl)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C
InChI
InChI=1S/C22H28ClFO4/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,24)17(26)10-20(16,3)22(12,28)18(27)11-23/h6-7,9,12,15-17,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1
InChIKey
FCSHDIVRCWTZOX-DVTGEIKXSA-N

Alternative Names

  • (11beta,16beta)-21-chloro-9-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
  • 21-chloro-9-fluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione
  • clobetasol
  • clobetasolum

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
2590
oboInOwl#hasDbXref
PMID:27012570
core#notation
CHEBI:205919

Additional References

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
2590
oboInOwl#hasDbXref
PMID:27012570
oboInOwl#id
CHEBI:205919
oboInOwl#hasAlternativeId
CHEBI:282071
generic_name
Clobetasol propionate micronized
brand_name_base
CLOBEX
brand_name
CLOBEX
product_ndc
82804-083
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_131809
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
labeler_name
Eyenovia, Inc.
marketing_start_date
20051027
application_number
ANDA211295
listing_expiration_date
20241231
spl_id
e0f7bc85-9c13-44df-9b37-c216ecfe3ffe
package_ndc
82804-083-30
package_marketing_start_date
20051027
package_description
100 g in 1 CAN (68462-608-94)
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
dosage_form
AEROSOL, FOAM
route
OPHTHALMIC
has_treatment
http://purl.obolibrary.org/obo/DOID_8741
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect10838
owl#annotatedSource
t145298
owl#someValuesFrom
t617118
active_ingredient_strength
.4625 mg/mL
active_ingredient_name
CLOBETASOL PROPIONATE
upc
0382804083305
spl_set_id
dfc58f73-e892-4fc3-8726-4e8d1546ebd3
core#notation
CHEBI:205919
brand_name_suffix
emollient formulation
pharm_class
Corticosteroid [EPC]
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rxcui
2180345
manufacturer_name
Eyenovia, Inc.
unii
779619577M