Discuss This Drug

vamorolone

CHEBI:CHEBI_228304

Definition

A 3-oxo-Delta(1),Delta(4)-steroid that is pregna-1,4,9(11)-trien-17-ol substituted by oxo, oxo, and hydroxy groups at positions 3, 20, and 21, respectively. It is approved by the FDA for the treatment of patients with Duchenne muscular dystrophy aged 2 years and older.

Chemical Information

Molecular Formula
C22H28O4
Molecular Mass
356.462
Charge
0
SMILES
[H][C@@]12C[C@@H](C)[C@](O)(C(=O)CO)[C@@]1(C)CC=C1[C@@]2([H])CCC2=CC(=O)C=C[C@]12C
InChI
InChI=1S/C22H28O4/c1-13-10-18-16-5-4-14-11-15(24)6-8-20(14,2)17(16)7-9-21(18,3)22(13,26)19(25)12-23/h6-8,11,13,16,18,23,26H,4-5,9-10,12H2,1-3H3/t13-,16-,18+,20+,21+,22+/m1/s1
InChIKey
ZYTXTXAMMDTYDQ-DGEXFFLYSA-N

Alternative Names

  • (16alpha)-17,21-dihydroxy-16-methylpregna-1,4,9(11)-triene-3,20-dione
  • 17,21-dihydroxy-16alpha-methylpregna-1,4,9(11)-triene-3,20-dione
  • 17alpha,21-dihydroxy-16alpha-methylpregna-1,4,9(11)-triene-3,20-dione
  • Agamree
  • vamorolona
  • vamorolone
  • vamorolonum
  • VBP 15
  • VBP-15
  • VBP15

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:228304
DRON_00010000
2669799
oboInOwl#hasDbXref
Wikipedia:Vamorolone

Additional References

Wikipedia:Vamorolone

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:228304
rxcui
2669810
active_ingredient_strength
1 kg/kg
package_marketing_start_date
13-DEC-23
manufacturer_name
Catalyst Pharmaceuticals, Inc.
active_ingredient_name
VAMOROLONE
spl_set_id
fb376f09-cf9c-42b5-b4dd-02d5bcd73211
upc
0369616265389
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
2669799
oboInOwl#hasDbXref
Wikipedia:Vamorolone
oboInOwl#id
CHEBI:228304
generic_name
Vamorolone
dosage_form
SUSPENSION
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
listing_expiration_date
20241231
route
ORAL
marketing_start_date
20231123
labeler_name
Purna Pharmaceuticals NV
product_ndc
46439-8771
spl_id
65d221bf-286e-4871-b659-202602494c9d
package_ndc
46439-8771-5
package_description
10 kg in 1 DRUM (46439-8771-5)
brand_name
AGAMREE
brand_name_base
AGAMREE
application_number
NDA215239
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_63562
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
has_treatment
http://purl.obolibrary.org/obo/DOID_0060943
owl#annotatedSource
t148823
owl#someValuesFrom
t4010890