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vamorolone

CHEBI:CHEBI_228304

Definition

A 3-oxo-Delta(1),Delta(4)-steroid that is pregna-1,4,9(11)-trien-17-ol substituted by oxo, oxo, and hydroxy groups at positions 3, 20, and 21, respectively. It is approved by the FDA for the treatment of patients with Duchenne muscular dystrophy aged 2 years and older.

Chemical Information

Molecular Formula
C22H28O4
Molecular Mass
356.462
Charge
0
SMILES
[H][C@@]12C[C@@H](C)[C@](O)(C(=O)CO)[C@@]1(C)CC=C1[C@@]2([H])CCC2=CC(=O)C=C[C@]12C
InChI
InChI=1S/C22H28O4/c1-13-10-18-16-5-4-14-11-15(24)6-8-20(14,2)17(16)7-9-21(18,3)22(13,26)19(25)12-23/h6-8,11,13,16,18,23,26H,4-5,9-10,12H2,1-3H3/t13-,16-,18+,20+,21+,22+/m1/s1
InChIKey
ZYTXTXAMMDTYDQ-DGEXFFLYSA-N

Alternative Names

  • (16alpha)-17,21-dihydroxy-16-methylpregna-1,4,9(11)-triene-3,20-dione
  • 17,21-dihydroxy-16alpha-methylpregna-1,4,9(11)-triene-3,20-dione
  • 17alpha,21-dihydroxy-16alpha-methylpregna-1,4,9(11)-triene-3,20-dione
  • Agamree
  • vamorolona
  • vamorolone
  • vamorolonum
  • VBP 15
  • VBP-15
  • VBP15

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
2669799
oboInOwl#hasDbXref
Wikipedia:Vamorolone
core#notation
CHEBI:228304

Additional References

Wikipedia:Vamorolone

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
2669799
oboInOwl#hasDbXref
Wikipedia:Vamorolone
oboInOwl#id
CHEBI:228304
core#notation
CHEBI:228304
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_63562
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_0060943
owl#annotatedSource
t148823
owl#someValuesFrom
t4010890