Discuss This Drug

bexagliflozin

CHEBI:CHEBI_229225

Definition

A C-glycosyl comprising of beta-D-glucose in which the anomeric hydroxy group is replaced by a 4-chloro-3-({4-[2-(cyclopropyloxy)ethoxy]phenyl}methyl)phenyl group. It is a sodium-glucose co-transporter 2 (SGLT2) inhibitor indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

Chemical Information

Molecular Formula
C24H29ClO7
Molecular Mass
464.940
Charge
0
SMILES
OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)C1=CC=C(Cl)C(CC2=CC=C(OCCOC3CC3)C=C2)=C1
InChI
InChI=1S/C24H29ClO7/c25-19-8-3-15(24-23(29)22(28)21(27)20(13-26)32-24)12-16(19)11-14-1-4-17(5-2-14)30-9-10-31-18-6-7-18/h1-5,8,12,18,20-24,26-29H,6-7,9-11,13H2/t20-,21-,22+,23-,24+/m1/s1
InChIKey
BTCRKOKVYTVOLU-SJSRKZJXSA-N

Alternative Names

  • (1S)-1,5-anhydro-1-(4-chloro-3-{4-[2-(cyclopropyloxy)ethoxy]benzyl}phenyl)-D-glucitol
  • (1S)-1,5-anhydro-1-C-[4-chloro-3-[[4-[2-(cyclopropyloxy)ethoxy]phenyl]methyl]phenyl]-D-glucitol
  • (2S,3R,4R,5S,6R)-2-(4-chloro-3-{4-[2-(cyclopropyloxy)ethoxy]benzyl}phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
  • (2S,3R,4R,5S,6R)-2-[4-chloro-3-({4-[2-(cyclopropyloxy)ethoxy]phenyl}methyl)phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol
  • bexagliflozin
  • bexagliflozina
  • bexagliflozine
  • bexagliflozinum
  • Brenzavvy
  • EGT 1442
  • EGT-1442
  • EGT0001442
  • EGT1442
  • THR 1442
  • THR-1442
  • THR1442

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
2627044
oboInOwl#hasDbXref
Wikipedia:Bexagliflozin
core#notation
CHEBI:229225

Additional References

Wikipedia:Bexagliflozin

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
2627044
oboInOwl#hasDbXref
Wikipedia:Bexagliflozin
oboInOwl#id
CHEBI:229225
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
listing_expiration_date
20241231
route
ORAL
dosage_form
POWDER
marketing_start_date
20240319
labeler_name
TheracosBio, LLC
generic_name
Bexagliflozin
brand_name
BRENZAVVY
brand_name_base
BRENZAVVY
product_ndc
51407-918
application_number
NDA214373
spl_id
1a3b96b0-10b5-9bb1-e063-6294a90ab279
package_ndc
51407-918-90
package_description
90 TABLET in 1 BOTTLE (51407-918-90)
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35674
core#notation
CHEBI:229225
rxcui
2637865
active_ingredient_strength
25 kg/25kg
package_marketing_start_date
26-SEP-18
nui
N0000187058
pharm_class_epc
Sodium-Glucose Cotransporter 2 Inhibitor [EPC]
pharm_class
Sodium-Glucose Transporter 2 Inhibitors [MoA]
pharm_class_moa
Sodium-Glucose Transporter 2 Inhibitors [MoA]
manufacturer_name
TheracosBio, LLC
active_ingredient_name
BEXAGLIFLOZIN
unii
EY00JF42FV
spl_set_id
1a3ba9d5-1009-bad0-e063-6294a90ac4cc
upc
0382381217414
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
owl#annotatedSource
t148799
owl#someValuesFrom
t3982771