ritlecitinib
CHEBI:CHEBI_229233
Definition
A pyrrolopyrimidine that is 7H-pyrrolo[2,3-d]pyrimidine substituted at position 4 by a [(3R,6S)-6-methyl-1-(prop-2-enoyl)piperidin-3-yl]amino group. It is a dual inhibitor of Janus kinase 3 and the TEC family of tyrosine kinases.
Chemical Information
- Molecular Formula
- C15H19N5O
- Molecular Mass
- 285.351
- Charge
- 0
- SMILES
- C[C@H]1CC[C@H](CN1C(=O)C=C)NC1=C2C=CNC2=NC=N1
- InChI
- InChI=1S/C15H19N5O/c1-3-13(21)20-8-11(5-4-10(20)2)19-15-12-6-7-16-14(12)17-9-18-15/h3,6-7,9-11H,1,4-5,8H2,2H3,(H2,16,17,18,19)/t10-,11+/m0/s1
- InChIKey
- CBRJPFGIXUFMTM-WDEREUQCSA-N
Alternative Names
- 1-[(2S,5R)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)piperidin-1-yl]prop-2-en-1-one
- PF 06651600
- PF-06651600
- PF06651600
- ritlecitinib
- ritlecitinibum
Drug Classification
-
pyrrolopyrimidineView Class →
CHEBI:38670
-
processed material
-
secondary amino compoundView Class →
CHEBI:50995
-
tertiary carboxamideView Class →
CHEBI:140326
-
acrylamidesView Class →
CHEBI:22216
-
N-acylpiperidineView Class →
CHEBI:48591
-
t147962
-
t148355
-
t148435
-
t148569
-
t148761
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 2641595
- oboInOwl#hasDbXref
- Wikipedia:Ritlecitinib
- core#notation
- CHEBI:229233
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- has_treatment
- http://purl.obolibrary.org/obo/DOID_987
- chebi#is_conjugate_acid_of
- http://purl.obolibrary.org/obo/CHEBI_229235
- owl#annotatedSource
- t148815
- owl#someValuesFrom
- t3983538
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 2641595
- oboInOwl#hasDbXref
- Wikipedia:Ritlecitinib
- oboInOwl#id
- CHEBI:229233
- core#notation
- CHEBI:229233
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_76617
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- chebi#is_conjugate_base_of
- http://purl.obolibrary.org/obo/CHEBI_229235
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class