Discuss This Drug

ritlecitinib

CHEBI:CHEBI_229233

Definition

A pyrrolopyrimidine that is 7H-pyrrolo[2,3-d]pyrimidine substituted at position 4 by a [(3R,6S)-6-methyl-1-(prop-2-enoyl)piperidin-3-yl]amino group. It is a dual inhibitor of Janus kinase 3 and the TEC family of tyrosine kinases.

Chemical Information

Molecular Formula
C15H19N5O
Molecular Mass
285.351
Charge
0
SMILES
C[C@H]1CC[C@H](CN1C(=O)C=C)NC1=C2C=CNC2=NC=N1
InChI
InChI=1S/C15H19N5O/c1-3-13(21)20-8-11(5-4-10(20)2)19-15-12-6-7-16-14(12)17-9-18-15/h3,6-7,9-11H,1,4-5,8H2,2H3,(H2,16,17,18,19)/t10-,11+/m0/s1
InChIKey
CBRJPFGIXUFMTM-WDEREUQCSA-N

Alternative Names

  • 1-[(2S,5R)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)piperidin-1-yl]prop-2-en-1-one
  • PF 06651600
  • PF-06651600
  • PF06651600
  • ritlecitinib
  • ritlecitinibum

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
2641595
oboInOwl#hasDbXref
Wikipedia:Ritlecitinib
core#notation
CHEBI:229233

Additional References

Wikipedia:Ritlecitinib

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

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chebi_ontology
DRON_00010000
2641595
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Wikipedia:Ritlecitinib
oboInOwl#id
CHEBI:229233
generic_name
ritlecitinib
product_type
DRUG FOR FURTHER PROCESSING
marketing_category
DRUG FOR FURTHER PROCESSING
listing_expiration_date
20251231
route
ORAL
active_ingredient_strength
50 mg/1
dosage_form
CAPSULE
pharm_class
Janus Kinase 3 Inhibitors [MoA]
marketing_start_date
20230613
package_marketing_start_date
13-JUN-23
labeler_name
U.S. Pharmaceuticals
manufacturer_name
U.S. Pharmaceuticals
brand_name
Litfulo
brand_name_base
Litfulo
product_ndc
63539-334
application_number
NDA215830
spl_id
1882f799-61b0-4813-965a-4910c4ae419c
active_ingredient_name
RITLECITINIB TOSYLATE
package_ndc
63539-334-28
package_description
28 CAPSULE in 1 BOTTLE (63539-334-28)
rxcui
2641607
unii
EAG4T1459K
spl_set_id
1882f799-61b0-4813-965a-4910c4ae419c
upc
0300690334288
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_76617
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CHEBI:229233
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http://purl.obolibrary.org/obo/DOID_987
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t148815
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t3983538