fezolinetant
CHEBI:CHEBI_229236
Definition
A triazolopyrazine that is 5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine substituted by 3-methyl-1,2,4-thiadiazol-5-yl, 4-fluorobenzoyl and methyl groups at positions 3, 7, and 8R, respectively. It is a prescription medicine used to reduce moderate to severe vasomotor symptoms due to menopause.
Chemical Information
- Molecular Formula
- C16H15FN6OS
- Molecular Mass
- 358.400
- Charge
- 0
- SMILES
- C[C@H]1N(CCN2C1=NN=C2C1=NC(C)=NS1)C(=O)C1=CC=C(F)C=C1
- InChI
- InChI=1S/C16H15FN6OS/c1-9-13-19-20-14(15-18-10(2)21-25-15)23(13)8-7-22(9)16(24)11-3-5-12(17)6-4-11/h3-6,9H,7-8H2,1-2H3/t9-/m1/s1
- InChIKey
- PPSNFPASKFYPMN-SECBINFHSA-N
Alternative Names
- (4-fluorophenyl)[(8R)-8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]methanone
- ESN 364
- ESN-364
- ESN364
- fezolinetant
- fezolinetantum
- Veozah
Drug Classification
-
benzamidesView Class →
CHEBI:22702
-
processed material
-
monofluorobenzenesView Class →
CHEBI:83575
-
thiadiazolesView Class →
CHEBI:38099
-
tertiary carboxamideView Class →
CHEBI:140326
-
triazolopyrazineView Class →
CHEBI:48277
-
t148222
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 2637134
- oboInOwl#hasDbXref
- Wikipedia:Fezolinetant
- core#notation
- CHEBI:229236
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 2637134
- oboInOwl#hasDbXref
- Wikipedia:Fezolinetant
- oboInOwl#id
- CHEBI:229236
- generic_name
- Fezolinetant
- rxcui
- 2637147
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT
- listing_expiration_date
- 20251231
- route
- ORAL
- dosage_form
- POWDER
- labeler_name
- Juzen Chemical Corporation
- manufacturer_name
- Astellas Pharma US, Inc.
- active_ingredient_strength
- 1 kg/kg
- marketing_start_date
- 20230703
- package_marketing_start_date
- 03-JUL-23
- product_ndc
- 51148-014
- spl_id
- fa44a704-081b-85d9-e053-6294a90a2cff
- active_ingredient_name
- FEZOLINETANT
- package_ndc
- 51148-014-01
- package_description
- 1 BAG in 1 CONTAINER (51148-014-01) / 93000 TABLET, FILM COATED in 1 BAG
- brand_name
- VEOZAH
- brand_name_base
- VEOZAH
- application_number
- NDA216578
- unii
- 83VNE45KXX
- spl_set_id
- cae9f798-24f9-4580-a4fc-e6c710cbda3c
- nui
- N0000194091
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_140482
- core#notation
- CHEBI:229236
- pharm_class_epc
- Neurokinin 3 Receptor Antagonist [EPC]
- pharm_class
- Neurokinin 3 Receptor Antagonists [MoA]
- pharm_class_moa
- Neurokinin 3 Receptor Antagonists [MoA]
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- owl#annotatedSource
- t148805
- owl#someValuesFrom
- t3983309