Discuss This Drug

Colchicine

CHEBI:CHEBI_23359

Definition

An alkaloid that is a carbotricyclic compound comprising 5,6,7,9-tetrahydrobenzo[a]heptalene having four methoxy substituents at the 1-, 2-, 3- and 10-positions as well as an oxo group at the 9-position and an acetamido group at the 7-position. It has been isolated from the plants belonging to genus Colchicum.

Chemical Information

Molecular Formula
C22H25NO6
Molecular Mass
399.43704
Charge
0
SMILES
COc1cc2CCC(NC(C)=O)c3cc(=O)c(OC)ccc3-c2c(OC)c1OC
InChI
InChI=1S/C22H25NO6/c1-12(24)23-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)
InChIKey
IAKHMKGGTNLKSZ-UHFFFAOYSA-N

Alternative Names

  • N-(1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl)acetamide

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
2683
oboInOwl#hasDbXref
Reaxys:2228812
core#notation
CHEBI:23359

Additional References

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

listing_expiration_date
20241231
labeler_name
AGEPHA Pharma USA, LLC
marketing_start_date
20230326
spl_id
ee9f131d-ab4c-19c7-e053-2995a90a15b4
application_number
ANDA209876
route
ORAL
package_ndc
61281-3600-4
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
2683
oboInOwl#hasDbXref
Reaxys:2228812
oboInOwl#id
CHEBI:23359
generic_name
Colchicine Tablets 0.5 mg
brand_name
LODOCO
brand_name_base
LODOCO
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
dosage_form
CAPSULE
product_ndc
61281-3600
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_61951
package_description
25 kg in 1 DRUM (61281-3600-4)
rxcui
2663988
manufacturer_name
AGEPHA Pharma USA, LLC
unii
HJ30158L57
spl_set_id
ff06d68f-d65f-d097-e053-6294a90a7e5f
package_marketing_start_date
20211203
core#notation
CHEBI:23359
pharm_class
P-Glycoprotein Interactions [MoA]
active_ingredient_strength
25 kg/25kg
active_ingredient_name
COLCHICEINE
nui
M0000713
pharm_class_epc
Alkaloid [EPC]
pharm_class_cs
Alkaloids [CS]
upc
0371205310301
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
Treatment
http://purl.obolibrary.org/obo/DOID_0040096
has_treatment
http://purl.obolibrary.org/obo/DOID_0081451
owl#annotatedSource
t148593
owl#someValuesFrom
t3382043