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Dibucaine

CHEBI:CHEBI_247956

Definition

A monocarboxylic acid amide that is the 2-(diethylamino)ethyl amide of 2-butoxyquinoline-4-carboxylic acid. One of the most potent and toxic of the long-acting local anesthetics, its parenteral use was restricted to spinal anesthesia. It is now generally only used (usually as the hydrochloride) in creams and ointments and in suppositories for temporary relief of pain and itching associated with skin and anorectal conditions.

Chemical Information

Molecular Formula
C20H29N3O2
Molecular Mass
343.46320
Charge
0
SMILES
CCCCOc1cc(C(=O)NCCN(CC)CC)c2ccccc2n1
InChI
InChI=1S/C20H29N3O2/c1-4-7-14-25-19-15-17(16-10-8-9-11-18(16)22-19)20(24)21-12-13-23(5-2)6-3/h8-11,15H,4-7,12-14H2,1-3H3,(H,21,24)
InChIKey
PUFQVTATUTYEAL-UHFFFAOYSA-N

Alternative Names

  • 2-butoxy-N-(2-(diethylamino)ethyl)cinchoninamide
  • 2-butoxy-N-(alpha-diethylaminoethyl)cinchoninamide
  • 2-butoxy-N-(beta-diethylaminoethyl)cinchoninamide
  • 2-butoxy-N-[2-(diethylamino)ethyl]-4-quinolinecarboxamide
  • 2-butoxy-N-[2-(diethylamino)ethyl]quinoline-4-carboxamide
  • 2-Butoxy-quinoline-4-carboxylic acid (2-diethylamino-ethyl)-amide
  • 2-butoxyquinoline-4-carboxylic acid diethylaminoethylamide
  • 2-N-butoxy-N-(2-diethylaminoethyl)cinchoninamide
  • alpha-butyloxycinchonic acid-gamma-diethylethylenediamine
  • alpha-butyloxycinchoninic acid diethylethylenediamide
  • cinchocaine
  • CINCHOCAINE
  • cinchocainum
  • cincocainio
  • dibucaine
  • Dibucaine
  • DIBUCAINE
  • dibucaine base
  • N-(2-(diethylamino)ethyl)-2-butoxycinchoninamide

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
3339
oboInOwl#hasDbXref
Wikipedia:Dibucaine
core#notation
CHEBI:247956

Additional References

Wikipedia:Dibucaine

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Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
3339
oboInOwl#hasDbXref
Wikipedia:Dibucaine
oboInOwl#id
CHEBI:247956
core#notation
CHEBI:247956
oboInOwl#hasAlternativeId
CHEBI:4500
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_48425
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_110324
owl#annotatedSource
t152191
owl#someValuesFrom
t599608