Discuss This Drug

Amifostine

CHEBI:CHEBI_2636

Definition

An organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy.

Chemical Information

Molecular Formula
C5H15N2O3PS
Molecular Mass
214.22404
Charge
0
SMILES
NCCCNCCSP(O)(O)=O
InChI
InChI=1S/C5H15N2O3PS/c6-2-1-3-7-4-5-12-11(8,9)10/h7H,1-6H2,(H2,8,9,10)
InChIKey
JKOQGQFVAUAYPM-UHFFFAOYSA-N

Alternative Names

  • amifostina
  • amifostine
  • Amifostine
  • amifostinum
  • Ethyol
  • S-{2-[(3-aminopropyl)amino]ethyl} dihydrogen thiophosphate

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
4126
oboInOwl#hasDbXref
Wikipedia:Amifostine
core#notation
CHEBI:2636

Additional References

Wikipedia:Amifostine

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Additional Attributes

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