Amiloride

CHEBI:CHEBI_2639

Definition

A member of the class of pyrazines resulting from the formal monoacylation of guanidine with the carboxy group of 3,5-diamino-6-chloropyrazine-2-carboxylic acid.

Chemical Information

Molecular Formula
C6H8ClN7O
Molecular Mass
229.62700
Charge
0
SMILES
NC(=N)NC(=O)c1nc(Cl)c(N)nc1N
InChI
InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15)
InChIKey
XSDQTOBWRPYKKA-UHFFFAOYSA-N

Alternative Names

  • 3,5-diamino-N-[amino(imino)methyl]-6-chloropyrazine-2-carboxamide
  • 3,5-diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide
  • amilorida
  • amiloride
  • Amiloride
  • amiloridum
  • N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:2639
DRON_00010000
644
oboInOwl#hasDbXref
Wikipedia:Amiloride

Additional References

Wikipedia:Amiloride

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

rxcui
977883
active_ingredient_name
AMILORIDE HYDROCHLORIDE ANHYDROUS
unii
7M458Q65S3
nui
M0002274
pharm_class_epc
Standardized Insect Venom Allergenic Extract [EPC]
pharm_class_pe
Increased IgG Production [PE]
active_ingredient_strength
2 [hp_X]/30mL
manufacturer_name
A-S Medication Solutions
package_marketing_start_date
19860512
package_ndc
63629-2114-1
package_description
1000 TABLET in 1 BOTTLE (63629-2114-1)
spl_set_id
18d551a9-ffc7-4b14-adbd-92d84aa8e966
upc
0349884117108
core#notation
CHEBI:2639
pharm_class
Bee Venoms [CS]
pharm_class_cs
Bee Venoms [CS]
pharm_class_moa
Aldosterone Antagonists [MoA]
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
644
oboInOwl#hasDbXref
Wikipedia:Amiloride
oboInOwl#id
CHEBI:2639
oboInOwl#hasAlternativeId
CHEBI:47210
product_type
BULK INGREDIENT
listing_expiration_date
20241231
route
ORAL
dosage_form
SOLUTION/ DROPS
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
labeler_name
A-S Medication Solutions
marketing_start_date
19860122
generic_name
Amiloride Hydrochloride
brand_name
Amiloride Hydrochloride
brand_name_base
Amiloride Hydrochloride
product_ndc
63629-2114
application_number
ANDA070346
spl_id
84adc61b-3ed3-452d-a1b8-d062869b263d
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_38633
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_84745
has_treatment
http://purl.obolibrary.org/obo/DOID_4044
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect11800
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_84745
owl#annotatedSource
t155579
owl#someValuesFrom
t1048576