Amiodarone

CHEBI:CHEBI_2663

Definition

A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.

Chemical Information

Molecular Formula
C25H29I2NO3
Molecular Mass
645.31160
Charge
0
SMILES
CCCCc1oc2ccccc2c1C(=O)c1cc(I)c(OCCN(CC)CC)c(I)c1
InChI
InChI=1S/C25H29I2NO3/c1-4-7-11-22-23(18-10-8-9-12-21(18)31-22)24(29)17-15-19(26)25(20(27)16-17)30-14-13-28(5-2)6-3/h8-10,12,15-16H,4-7,11,13-14H2,1-3H3
InChIKey
IYIKLHRQXLHMJQ-UHFFFAOYSA-N

Alternative Names

  • (2-butyl-1-benzofuran-3-yl){4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl}methanone
  • 2-Butyl-3-(3,5-diiodo-4-(2-diethylaminoethoxy)benzoyl)benzofuran
  • 2-Butyl-3-benzofuranyl 4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl ketone
  • 2-n-Butyl-3',5'-diiodo-4'-N-diethylaminoethoxy-3-benzoylbenzofuran
  • amiodarona
  • Amiodarone
  • amiodaronum

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
703
oboInOwl#hasDbXref
Wikipedia:Amiodarone
core#notation
CHEBI:2663

Additional References

Wikipedia:Amiodarone

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
dosage_form
INJECTION, SOLUTION
marketing_start_date
19961016
labeler_name
Zhejiang Poly Pharm. Co., Ltd.
application_number
ANDA077161
product_ndc
72888-060
listing_expiration_date
20241231
route
INTRAVENOUS
spl_id
d2c4aab0-2e5d-84b7-e053-2a95a90aef8b
package_ndc
14335-270-01
package_description
10 kg in 1 DRUM (14335-270-01)
has_treatment
http://purl.obolibrary.org/obo/DOID_0070535
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect11835
owl#annotatedSource
t155631
owl#someValuesFrom
t3000375
package_marketing_start_date
16-OCT-96
manufacturer_name
Zhejiang Poly Pharm. Co., Ltd.
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
703
oboInOwl#hasDbXref
Wikipedia:Amiodarone
oboInOwl#id
CHEBI:2663
generic_name
Amiodarone HCl
brand_name
Amiodarone hydrochloride
brand_name_base
Amiodarone hydrochloride
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35554
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
BFO_0000053
http://purl.obolibrary.org/obo/DRON_00723854
core#notation
CHEBI:2663
pharm_class
Cytochrome P450 2C9 Inhibitors [MoA]
upc
0362135578305
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rxcui
1663248
active_ingredient_strength
900 mg/18mL
active_ingredient_name
AMIODARONE
unii
976728SY6Z
spl_set_id
337c5695-e3f8-41c6-a088-a492d5c60215