Discuss This Drug

Amitriptyline

CHEBI:CHEBI_2666

Definition

An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.

Chemical Information

Molecular Formula
C20H23N
Molecular Mass
277.40336
Charge
0
SMILES
CN(C)CCC=C1c2ccccc2CCc2ccccc12
InChI
InChI=1S/C20H23N/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20/h3-6,8-12H,7,13-15H2,1-2H3
InChIKey
KRMDCWKBEZIMAB-UHFFFAOYSA-N

Alternative Names

  • 10,11-dihydro-5-(gamma-dimethylaminopropylidene)-5H-dibenzo(a,d)cycloheptene
  • 10,11-dihydro-N,N-dimethyl-5H-dibenzo(a,d)heptalene-Delta(5),gamma-propylamine
  • 3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine
  • 3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)-N,N-dimethylpropan-1-amine
  • 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethylpropan-1-amine
  • 5-(3-dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptatriene
  • 5-(3-dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptene
  • 5-(gamma-dimethylaminopropylidene)-5H-dibenzo[a,d][1,4]cycloheptadiene
  • Amitriptylin
  • Amitriptyline

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
704
oboInOwl#hasDbXref
Wikipedia:Amitriptyline
core#notation
CHEBI:2666

Additional References

Wikipedia:Amitriptyline

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

product_ndc
0904-7184
listing_expiration_date
20241231
spl_id
f1a131b6-45b4-be60-e053-2a95a90a2932
marketing_start_date
20231109
product_type
BULK INGREDIENT
dosage_form
TABLET, COATED
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
route
ORAL
package_ndc
51927-1603-0
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
704
oboInOwl#hasDbXref
Wikipedia:Amitriptyline
oboInOwl#id
CHEBI:2666
generic_name
AMITRIPTYLINE
brand_name
AMITRIPTYLINE HCL
brand_name_base
AMITRIPTYLINE HCL
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35640
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
BFO_0000053
http://purl.obolibrary.org/obo/DRON_00723855
chebi#has_parent_hydride
http://purl.obolibrary.org/obo/CHEBI_35642
package_description
30 TABLET, FILM COATED in 1 BOTTLE (71335-0395-1)
has_treatment
http://purl.obolibrary.org/obo/DOID_631
labeler_name
Preferred Pharamaceuticals Inc.
application_number
ANDA216243
rxcui
856853
manufacturer_name
Preferred Pharamaceuticals Inc.
unii
26LUD4JO9K
spl_set_id
abf6a3f5-0df9-4b23-995d-63b973ef80c1
package_marketing_start_date
20230327
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect11856
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_7640
owl#annotatedSource
t155643
owl#someValuesFrom
t3006107
active_ingredient_strength
100 kg/100kg
pharm_class
Tricyclic Antidepressant [EPC]
active_ingredient_name
AMITRIPTYLINE HYDROCHLORIDE
upc
0368071365634
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
core#notation
CHEBI:2666