trimethobenzamide
CHEBI:CHEBI_27796
Definition
The amide obtained by formal condensation of 3,4,5-trihydroxybenzoic acid with 4-[2-(N,N-dimethylamino)ethoxy]benzylamine. It is used to prevent nausea and vomitting in humans.
Chemical Information
- Molecular Formula
- C21H28N2O5
- Molecular Mass
- 388.45740
- Charge
- 0
- SMILES
- COc1cc(cc(OC)c1OC)C(=O)NCc1ccc(OCCN(C)C)cc1
- InChI
- InChI=1S/C21H28N2O5/c1-23(2)10-11-28-17-8-6-15(7-9-17)14-22-21(24)16-12-18(25-3)20(27-5)19(13-16)26-4/h6-9,12-13H,10-11,14H2,1-5H3,(H,22,24)
- InChIKey
- FEZBIKUBAYAZIU-UHFFFAOYSA-N
Alternative Names
- N-[[4-(2-dimethylaminoethoxy)phenyl]methyl]-3,4,5-trimethoxybenzamide
- N-{4-[2-(dimethylamino)ethoxy]benzyl}-3,4,5-trimethoxybenzamide
- trimethobenzamide
- trimethobenzamidum
- trimetobenzamida
Drug Classification
-
benzamidesView Class →
CHEBI:22702
-
tertiary amino compoundView Class →
CHEBI:50996
-
t159131
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 38685
- oboInOwl#hasDbXref
- Wikipedia:Trimethobenzamide
- core#notation
- CHEBI:27796
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 38685
- oboInOwl#hasDbXref
- Wikipedia:Trimethobenzamide
- oboInOwl#hasAlternativeId
- CHEBI:9730
- oboInOwl#id
- CHEBI:27796
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT
- listing_expiration_date
- 20241231
- route
- INTRAMUSCULAR
- dosage_form
- CAPSULE
- labeler_name
- Henry Schein, Inc
- marketing_start_date
- 20110117
- generic_name
- trimethobenzamide hydrochloride
- brand_name
- Tigan
- brand_name_base
- Tigan
- product_ndc
- 42023-119
- application_number
- ANDA076546
- spl_id
- 8528e4f6-52eb-4f5c-a440-ffcb1096cc87
- package_ndc
- 42023-119-25
- package_description
- 25 VIAL, SINGLE-DOSE in 1 TRAY (42023-119-25) / 2 mL in 1 VIAL, SINGLE-DOSE
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_50919
- core#notation
- CHEBI:27796
- rxcui
- 1726682
- pharm_class
- Emesis Suppression [PE]
- active_ingredient_strength
- 10 kg/10kg
- manufacturer_name
- Henry Schein, Inc
- package_marketing_start_date
- 20110117
- active_ingredient_name
- TRIMETHOBENZAMIDE HYDROCHLORIDE
- unii
- WDQ5P1SX7Q
- spl_set_id
- 7da90678-b229-4ad6-9193-2b8a3e9ba695
- upc
- 0343386660247
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect12796
- owl#annotatedSource
- t159102
- owl#someValuesFrom
- t1024564