Discuss This Drug

Pentostatin

CHEBI:CHEBI_27834

Definition

A member of the class of coformycins that is coformycin in which the hydroxy group at position 2' is replaced with a hydrogen. It is a drug used for the treatment of hairy cell leukaemia.

Chemical Information

Molecular Formula
C11H16N4O4
Molecular Mass
268.273
Charge
0
SMILES
OC[C@H]1O[C@H](C[C@@H]1O)N1C=NC2=C1N=CNC[C@H]2O
InChI
InChI=1S/C11H16N4O4/c16-3-8-6(17)1-9(19-8)15-5-14-10-7(18)2-12-4-13-11(10)15/h4-9,16-18H,1-3H2,(H,12,13)/t6-,7+,8+,9+/m0/s1
InChIKey
FPVKHBSQESCIEP-JQCXWYLXSA-N

Alternative Names

  • pentostatin
  • (8R)-3-(2-deoxy-beta-D-erythro-pentofuranosyl)-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol
  • 2'-deoxycoformycin
  • CI 825
  • CI-825
  • CI825
  • co-vidarabine
  • deoxycoformycin
  • Nipent
  • PD 81565
  • PD-81565
  • PD-ADI
  • PD81565
  • pentostatina
  • pentostatine
  • pentostatinum
  • YK-176

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Pentostatin
DRON_00010000
8011
core#notation
CHEBI:27834

Additional References

Wikipedia:Pentostatin

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Pentostatin
DRON_00010000
8011
oboInOwl#hasAlternativeId
CHEBI:4406
oboInOwl#id
CHEBI:27834
brand_name
Nipent
brand_name_base
Nipent
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
listing_expiration_date
20241231
dosage_form
INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION
marketing_start_date
20091102
labeler_name
Corden Pharma Boulder, Inc.
generic_name
PENTOSTATIN
product_ndc
42533-109
application_number
NDA020122
spl_id
09956557-edf2-48db-e063-6294a90a7dc8
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50445
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_229687
core#notation
CHEBI:27834
rxcui
105607
pharm_class_moa
Nucleic Acid Synthesis Inhibitors [MoA]
pharm_class
Nucleoside Metabolic Inhibitor [EPC]
pharm_class_epc
Nucleoside Metabolic Inhibitor [EPC]
route
INTRAVENOUS
active_ingredient_strength
1 kg/kg
nui
N0000175595
package_marketing_start_date
02-NOV-09
manufacturer_name
Hospira, Inc.
active_ingredient_name
PENTOSTATIN
package_ndc
42533-109-01
package_description
160 g in 1 CONTAINER (42533-109-01)
unii
395575MZO7
spl_set_id
674e0e6d-46ed-4868-9196-04019d667716
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_285
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_229687
owl#someValuesFrom
t3019771
owl#annotatedSource
t162715