Discuss This Drug

rifampicin

CHEBI:CHEBI_28077

Definition

A member of the class of rifamycins that is a a semisynthetic antibiotic derived from Amycolatopsis rifamycinica (previously known as Amycolatopsis mediterranei and Streptomyces mediterranei).

Chemical Information

Molecular Formula
C43H58N4O12
Molecular Mass
822.94020
Charge
0
SMILES
CO[C@H]1\C=C\O[C@@]2(C)Oc3c(C)c(O)c4c(O)c(NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)c(\C=N\N1CCN(C)CC1)c(O)c4c3C2=O
InChI
InChI=1S/C43H58N4O12/c1-21-12-11-13-22(2)42(55)45-33-28(20-44-47-17-15-46(9)16-18-47)37(52)30-31(38(33)53)36(51)26(6)40-32(30)41(54)43(8,59-40)57-19-14-29(56-10)23(3)39(58-27(7)48)25(5)35(50)24(4)34(21)49/h11-14,19-21,23-25,29,34-35,39,49-53H,15-18H2,1-10H3,(H,45,55)/b12-11+,19-14+,22-13-,44-20+/t21-,23+,24+,25+,29-,34-,35+,39+,43-/m0/s1
InChIKey
JQXXHWHPUNPDRT-WLSIYKJHSA-N

Alternative Names

  • 3-(((4-Methyl-1-piperazinyl)imino)methyl)rifamycin SV
  • RFP
  • rifamcin
  • rifampicin
  • Rifampicin
  • rifampicina
  • rifampicinum
  • Rifampin
  • (7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15,17,27,29-pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-26-{(E)-[(4-methylpiperazin-1-yl)imino]methyl}-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.1(4,7).0(5,28)]triaconta-1(28),1(29),2,4,9,19,21,25,27-nonaen-13-yl acetate

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:28077
DRON_00010000
9384
oboInOwl#hasDbXref
Wikipedia:Rifampicin

Additional References

Wikipedia:Rifampicin

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:28077
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
9384
oboInOwl#hasDbXref
Wikipedia:Rifampicin
oboInOwl#hasAlternativeId
CHEBI:8858
oboInOwl#id
CHEBI:28077
generic_name
Rifampicin
listing_expiration_date
20241231
dosage_form
POWDER
marketing_start_date
20220719
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
active_ingredient_strength
1 kg/kg
active_ingredient_name
RIFAMPIN
labeler_name
OLON ACTIVE PHARMACEUTICAL INGREDIENTS INDIA PRIVATE LIMITED
product_ndc
73005-0006
spl_id
e414a78a-a802-34fc-e053-2a95a90af58f
package_ndc
73005-0006-1
package_description
1 BAG in 1 DRUM (73005-0006-1) / 1 BAG in 1 BAG / 1 BAG in 1 BAG / 50 kg in 1 BAG
package_marketing_start_date
19-JUL-22
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_77318
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#is_tautomer_of
http://purl.obolibrary.org/obo/CHEBI_71365
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
Antibiotic
http://purl.obolibrary.org/obo/DOID_0050003
has_treatment
http://purl.obolibrary.org/obo/DOID_0070232
owl#annotatedSource
t162767
owl#someValuesFrom
t3088505