Discuss This Drug

Nitroglycerin

CHEBI:CHEBI_28787

Definition

A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.

Chemical Information

Molecular Formula
C3H5N3O9
Molecular Mass
227.08650
Charge
0
SMILES
[O-][N+](=O)OCC(CO[N+]([O-])=O)O[N+]([O-])=O
InChI
InChI=1S/C3H5N3O9/c7-4(8)13-1-3(15-6(11)12)2-14-5(9)10/h3H,1-2H2
InChIKey
SNIOPGDIGTZGOP-UHFFFAOYSA-N

Alternative Names

  • nitroglycerol
  • 1,2,3-propanetrioltrinitrate
  • 1,2,3-propanetriyl nitrate
  • 1,2,3-trinitrooxypropane
  • glycerin trinitrate
  • glycerol trinitrate
  • glycerol, nitric acid triester
  • Glyceryl trinitrate
  • Minitran
  • Natispray
  • NG
  • Nitro-Dur
  • Nitroglycerin
  • nitroglycerine
  • Nitrolingual
  • Nitromist
  • Nitrostat
  • propane-1,2,3-triyl trinitrate
  • Rectogesic
  • Transderm Nitro
  • trinitroglycerin
  • trinitroglycerol

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
4917
oboInOwl#hasDbXref
Wikipedia:Nitroglycerin
core#notation
CHEBI:28787

Additional References

Wikipedia:Nitroglycerin

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

rxcui
705129
active_ingredient_strength
40 mg/100mL
active_ingredient_name
NITROGLYCERIN
unii
G59M7S0WS3
spl_set_id
160b85ac-d964-463b-9f1e-1429f14ed318
package_description
1 BOTTLE in 1 CARTON (0071-0419-24) / 100 TABLET in 1 BOTTLE
package_ndc
60429-840-01
marketing_category
BULK INGREDIENT
listing_expiration_date
20241231
labeler_name
Trupharma, LLC
marketing_start_date
20170819
application_number
ANDA217970
product_type
BULK INGREDIENT
dosage_form
PELLET
product_ndc
45802-210
manufacturer_name
Trupharma, LLC
package_marketing_start_date
20190701
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
4917
oboInOwl#hasDbXref
Wikipedia:Nitroglycerin
oboInOwl#hasAlternativeId
CHEBI:7595
oboInOwl#id
CHEBI:28787
generic_name
Nitroglycerin in MCT oil
brand_name
NITROSTAT
brand_name_base
NITROSTAT
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_63490
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
route
TRANSDERMAL
spl_id
160b85ac-d964-463b-9f1e-1429f14ed318
core#notation
CHEBI:28787
nui
N0000009909
upc
0382804077250
pharm_class_epc
Nitrate Vasodilator [EPC]
pharm_class
Nitrates [CS]
pharm_class_pe
Vasodilation [PE]
pharm_class_cs
Nitrates [CS]
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect14624
owl#annotatedSource
t166324
owl#someValuesFrom
t3103304
has_treatment
http://purl.obolibrary.org/obo/DOID_5850