Tobramycin
CHEBI:CHEBI_28864
Definition
A amino cyclitol glycoside that is kanamycin B lacking the 3-hydroxy substituent from the 2,6-diaminoglucose ring.
Chemical Information
- Molecular Formula
- C18H37N5O9
- Molecular Mass
- 467.51450
- Charge
- 0
- SMILES
- NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O
- InChI
- InChI=1S/C18H37N5O9/c19-3-9-8(25)2-7(22)17(29-9)31-15-5(20)1-6(21)16(14(15)28)32-18-13(27)11(23)12(26)10(4-24)30-18/h5-18,24-28H,1-4,19-23H2/t5-,6+,7+,8-,9+,10+,11-,12+,13+,14-,15+,16-,17+,18+/m0/s1
- InChIKey
- NLVFBUXFDBBNBW-PBSUHMDJSA-N
Alternative Names
- (1S,2S,3R,4S,6R)-4,6-diamino-3-(2,6-diamino-2,3,6-trideoxy-alpha-D-ribo-hexopyranosyloxy)-2-hydroxycyclohexyl 3-amino-3-deoxy-alpha-D-glucopyranoside
- 3'-Deoxykanamycin B
- Nebramycin 6
- Nebramycin factir 6
- O-3-Amino-3-deoxy-alpha-D-glucopyranosyl-(1-4)-O-(2,6-diamino-2,3,6-trideoxy-alpha-D-ribohexopyranosyl-(1-4))-2-deoxy-D-streptamine
- Tobracin (TN)
- Tobramycin
- Tobrex (TN)
Drug Classification
-
amino cyclitol glycosideView Class →
CHEBI:22479
-
t165566
-
t165727
-
t165879
-
t166117
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 10627
- oboInOwl#hasDbXref
- Wikipedia:Tobramycin
- core#notation
- CHEBI:28864
Additional References
Wikipedia:Tobramycin
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- brand_name_base
- Tobradex ST
- product_ndc
- 51846-1012
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
- labeler_name
- Eyevance Pharmaceuticals, LLC
- dosage_form
- INHALANT
- application_number
- ANDA212848
- listing_expiration_date
- 20241231
- marketing_start_date
- 20000912
- spl_id
- 073efb10-3907-461c-a473-ea4fe9493170
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 10627
- oboInOwl#hasDbXref
- Wikipedia:Tobramycin
- oboInOwl#hasAlternativeId
- CHEBI:9610
- oboInOwl#id
- CHEBI:28864
- generic_name
- tobramycin / dexamethasone
- brand_name
- Tobradex ST
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_27026
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- chebi#has_functional_parent
- http://purl.obolibrary.org/obo/CHEBI_28098
- chebi#is_conjugate_base_of
- http://purl.obolibrary.org/obo/CHEBI_73678
- has_treatment
- http://purl.obolibrary.org/obo/DOID_11184
- package_description
- 1 kg in 1 CARTON (51846-1012-0)
- package_ndc
- 0574-4031-25
- package_marketing_start_date
- 10-APR-13
- route
- OPHTHALMIC
- rxcui
- 1661567
- manufacturer_name
- Eyevance Pharmaceuticals, LLC
- core#notation
- CHEBI:28864
- pharm_class_moa
- Corticosteroid Hormone Receptor Agonists [MoA]
- pharm_class
- Aminoglycosides [CS]
- pharm_class_epc
- Aminoglycoside Antibacterial [EPC]
- nui
- M0000946
- active_ingredient_strength
- 7 kg/7kg
- pharm_class_cs
- Aminoglycosides [CS]
- upc
- 0370756617440
- brand_name_suffix
- Inhalation Solution Pak
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- active_ingredient_name
- TOBRAMYCIN
- unii
- VZ8RRZ51VK
- spl_set_id
- c6f9c6b1-2c45-4f6b-a1fb-e55d74fc04c3
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect14783
- chebi#is_conjugate_acid_of
- http://purl.obolibrary.org/obo/CHEBI_73678
- owl#annotatedSource
- t166315
- owl#someValuesFrom
- t3362917