Discuss This Drug

Melphalan

CHEBI:CHEBI_28876

Definition

A phenylalanine derivative comprising L-phenylalanine having [bis(2-chloroethyl)amino group at the 4-position on the phenyl ring.

Chemical Information

Molecular Formula
C13H18Cl2N2O2
Molecular Mass
305.20000
Charge
0
SMILES
N[C@@H](Cc1ccc(cc1)N(CCCl)CCCl)C(O)=O
InChI
InChI=1S/C13H18Cl2N2O2/c14-5-7-17(8-6-15)11-3-1-10(2-4-11)9-12(16)13(18)19/h1-4,12H,5-9,16H2,(H,18,19)/t12-/m0/s1
InChIKey
SGDBTWWWUNNDEQ-LBPRGKRZSA-N

Alternative Names

  • 3-(p-(Bis(2-chloroethyl)amino)phenyl)-L-alanine
  • 3-p-(Di(2-chloroethyl)amino)-phenyl-L-alanine
  • 4-(Bis(2-chloroethyl)amino)-L-phenylalanine
  • 4-[bis(2-chloroethyl)amino]-L-phenylalanine
  • L-3-(p-(Bis(2-chloroethyl)amino)phenyl)alanine
  • L-PAM
  • L-Phenylalanine mustard
  • L-Sarcolysine
  • melfalano
  • melphalan
  • melphalanum
  • p-Bis(beta-chloroethyl)aminophenylalanine
  • p-Di-(2-chloroethyl)amino-L-phenylalanine
  • p-L-Sarcolysin
  • p-N-Bis(2-chloroethyl)amino-L-phenylalanine
  • p-N,N-bis(2-chloroethyl)amino-L-phenylalanine
  • Phenylalanine mustard
  • Phenylalanine nitrogen mustard

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:28876
oboInOwl#hasDbXref
Wikipedia:Melphalan
DRON_00010000
6718

Additional References

Wikipedia:Melphalan

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:28876
pharm_class
Alkylating Drug [EPC]
upc
0343598028354
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
route
INTRAVENOUS
package_ndc
59981-016-50
package_description
500 g in 1 BAG (59981-016-50)
spl_id
08f08d32-6fb1-8763-e063-6294a90a1882
dosage_form
INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
listing_expiration_date
20241231
marketing_start_date
20130110
labeler_name
Chemcon, GmbH
application_number
ANDA209197
product_ndc
25021-258
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Melphalan
DRON_00010000
6718
oboInOwl#hasAlternativeId
CHEBI:6742
prefixIRI
CHEBI:28876
oboInOwl#id
CHEBI:28876
generic_name
Melphalan HCl
brand_name
Melphalan hydrochloride
brand_name_base
Melphalan hydrochloride
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_88188
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
rxcui
1745090
package_marketing_start_date
12-OCT-10
manufacturer_name
Arthur Group LLC
active_ingredient_strength
50 mg/10mL
spl_set_id
dab93975-0587-4f12-848c-9130bb02d036
active_ingredient_name
MELPHALAN
unii
1VXP4V453T
RO_0001022
http://purl.obolibrary.org/obo/DOID_0040066
has_treatment
http://purl.obolibrary.org/obo/DOID_4912
owl#annotatedSource
t166346
owl#someValuesFrom
t3003688