desloratadine
CHEBI:CHEBI_291342
Definition
Loratadine in which the ethoxycarbonyl group attached to the piperidine ring is replaced by hydrogen. The major metabolite of loratidine, desloratadine is an antihistamine which is used for the symptomatic relief of allergic conditions including rhinitis and chronic urticaria. It does not readily enter the central nervous system, so does not cause drowsiness.
Chemical Information
- Molecular Formula
- C19H19ClN2
- Molecular Mass
- 310.82100
- Charge
- 0
- SMILES
- Clc1ccc2c(CCc3cccnc3C2=C2CCNCC2)c1
- InChI
- InChI=1S/C19H19ClN2/c20-16-5-6-17-15(12-16)4-3-14-2-1-9-22-19(14)18(17)13-7-10-21-11-8-13/h1-2,5-6,9,12,21H,3-4,7-8,10-11H2
- InChIKey
- JAUOIFJMECXRGI-UHFFFAOYSA-N
Alternative Names
- 8-chloro-11-(piperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
- 8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
- 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridine
- descarboethoxyloratadine
- desloratadine
- DESLORATADINE
Drug Classification
-
benzocycloheptapyridineView Class →
CHEBI:48593
-
t168532
-
t169152
-
t169582
-
t169852
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- core#notation
- CHEBI:291342
- DRON_00010000
- 275635
- oboInOwl#hasDbXref
- Wikipedia:Desloratadine
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- listing_expiration_date
- 20241231
- route
- ORAL
- marketing_start_date
- 20060901
- spl_id
- 89db0779-31d6-4916-8be1-dd4064e367ba
- package_ndc
- 65015-698-61
- package_description
- 100 kg in 1 DRUM (65015-698-61)
- labeler_name
- A-S Medication Solutions
- core#notation
- CHEBI:291342
- active_ingredient_name
- PSEUDOEPHEDRINE SULFATE
- rxcui
- 1112250
- active_ingredient_strength
- 25 kg/25kg
- pharm_class_moa
- Histamine H1 Receptor Antagonists [MoA]
- pharm_class
- alpha-Adrenergic Agonist [EPC]
- pharm_class_epc
- Histamine-1 Receptor Antagonist [EPC]
- manufacturer_name
- Belcher Pharmaceuticals,LLC
- package_marketing_start_date
- 26-JAN-15
- unii
- FVF865388R
- nui
- N0000175587
- spl_set_id
- 2a90b899-7746-43dc-ac8a-e754428eb30c
- upc
- 0368180153016
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 275635
- oboInOwl#hasDbXref
- Wikipedia:Desloratadine
- oboInOwl#id
- CHEBI:291342
- generic_name
- desloratadine and pseudoephedrine sulfate
- brand_name
- CLARINEX-D 12 HOUR
- brand_name_base
- CLARINEX-D 12 HOUR
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
- dosage_form
- TABLET, ORALLY DISINTEGRATING
- product_ndc
- 65015-698
- application_number
- ANDA078367
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_37955
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- has_treatment
- http://purl.obolibrary.org/obo/DOID_8892
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect14957
- chebi#has_functional_parent
- http://purl.obolibrary.org/obo/CHEBI_6538
- owl#annotatedSource
- t169729
- owl#someValuesFrom
- t3004703