Discuss This Drug

Auranofin

CHEBI:CHEBI_2922

Definition

An S-glycosyl compound consisting of 2,3,4,6-tetra-O-acetyl-1-thio-beta-D-glucopyranose with the sufur atom coordinated to (triethylphosphoranylidene)gold. It is administered orally for the treatment of active progressive rheumatoid arthritis.

Chemical Information

Molecular Formula
C20H34AuO9PS
Molecular Mass
678.48400
Charge
0
SMILES
CC[P+](CC)(CC)[Au-]S[C@@H]1O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1OC(C)=O
InChI
InChI=1S/C14H20O9S.C6H15P.Au/c1-6(15)19-5-10-11(20-7(2)16)12(21-8(3)17)13(14(24)23-10)22-9(4)18;1-4-7(5-2)6-3;/h10-14,24H,5H2,1-4H3;4-6H2,1-3H3;/q;;+1/p-1/t10-,11-,12+,13-,14+;;/m1../s1
InChIKey
AUJRCFUBUPVWSZ-XTZHGVARSA-M

Alternative Names

  • (1-Thio-beta-D-glucopyranosato)(triethylphosphine)gold 2,3,4,6-tetraacetate
  • (2,3,4,6-tetra-O-acetyl-1-thio-beta-D-glucopyranosato-kappaS(1))(triethylphosphine)gold
  • 2,3,4,6-Tetra-O-acetyl-1-thio-beta-D-glucopyranosato-S (triethylphosphine)gold
  • auranofin
  • auranofina
  • auranofine
  • auranofinum
  • Ridaura
  • Triethylphosphine gold

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
1227
oboInOwl#hasDbXref
Wikipedia:Auranofin
core#notation
CHEBI:2922

Additional References

Wikipedia:Auranofin

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
1227
generic_name
Auranofin
oboInOwl#hasDbXref
Wikipedia:Auranofin
oboInOwl#id
CHEBI:2922
core#notation
CHEBI:2922
rxcui
213510
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
listing_expiration_date
20241231
route
ORAL
dosage_form
CAPSULE
marketing_start_date
20020101
package_marketing_start_date
01-JAN-02
active_ingredient_strength
1 kg/kg
labeler_name
Sebela Pharmaceuticals Inc.
manufacturer_name
Sebela Pharmaceuticals Inc.
brand_name
RIDAURA
brand_name_base
RIDAURA
product_ndc
49812-0067
application_number
NDA018689
spl_id
efe5f0bd-5093-6e8a-e053-2995a90a3190
active_ingredient_name
AURANOFIN
package_ndc
49812-0067-1
package_description
1 CONTAINER in 1 CONTAINER (49812-0067-1) / 1 kg in 1 CONTAINER
unii
3H04W2810V
spl_set_id
43ba3de1-ab2e-06f6-e054-00144ff8d46c
upc
0354766093067
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_64670
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http://purl.obolibrary.org/obo/chebi#3_STAR
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
owl#annotatedSource
t169851
owl#someValuesFrom
t854839