Discuss This Drug

Azathioprine

CHEBI:CHEBI_2948

Definition

A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Chemical Information

Molecular Formula
C9H7N7O2S
Molecular Mass
277.26386
Charge
0
SMILES
Cn1cnc(c1Sc1ncnc2nc[nH]c12)[N+]([O-])=O
InChI
InChI=1S/C9H7N7O2S/c1-15-4-14-7(16(17)18)9(15)19-8-5-6(11-2-10-5)12-3-13-8/h2-4H,1H3,(H,10,11,12,13)
InChIKey
LMEKQMALGUDUQG-UHFFFAOYSA-N

Alternative Names

  • 6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-1H-purine
  • 6-(1'-Methyl-4'-nitro-5'-imidazolyl)-mercaptopurine
  • 6-[(1-methyl-4-nitro-1H-imidazol-5-yl)sulfanyl]-7H-purine
  • Imuran (TN)

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:2948
oboInOwl#hasDbXref
Wikipedia:Azathioprine
DRON_00010000
1256

Additional References

Wikipedia:Azathioprine

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
listing_expiration_date
20241231
route
INTRAVENOUS
dosage_form
INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION
marketing_start_date
19930219
labeler_name
Glenmark Pharmaceuticals, Inc
application_number
ANDA077621
spl_id
ecac2eec-9ad7-9193-e053-2995a90abf50
package_ndc
48954-909-00
product_ndc
68382-120
package_description
1 BAG in 1 DRUM (48954-909-00) / 50 kg in 1 BAG
rxcui
404476
package_marketing_start_date
19-FEB-93
manufacturer_name
Glenmark Pharmaceuticals, Inc
active_ingredient_name
AZATHIOPRINE SODIUM
unii
AM94R510MS
spl_set_id
d72ede2c-1a9b-4717-80a7-b76a6a499936
core#notation
CHEBI:2948
active_ingredient_strength
100 mg/10mL
pharm_class_moa
Nucleic Acid Synthesis Inhibitors [MoA]
pharm_class
Purines [CS]
nui
M0018169
pharm_class_cs
Purines [CS]
upc
0368682231014
pharm_class_epc
Purine Antimetabolite [EPC]
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Azathioprine
DRON_00010000
1256
generic_name
Azathioprine Sodium
brand_name
Azathioprine Sodium
brand_name_base
Azathioprine Sodium
oboInOwl#id
CHEBI:2948
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50266
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
has_treatment
http://purl.obolibrary.org/obo/DOID_2556
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_108400
owl#annotatedSource
t173236
owl#someValuesFrom
t3004441