Baclofen
CHEBI:CHEBI_2972
Definition
A monocarboxylic acid that is butanoic acid substituted by an amino group at position 4 and a 4-chlorophenyl group at position 3. It acts as a central nervous system depressant, GABA agonist and muscle relaxant.
Chemical Information
- Molecular Formula
- C10H12ClNO2
- Molecular Mass
- 213.66100
- Charge
- 0
- SMILES
- NCC(CC(O)=O)c1ccc(Cl)cc1
- InChI
- InChI=1S/C10H12ClNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14)
- InChIKey
- KPYSYYIEGFHWSV-UHFFFAOYSA-N
Alternative Names
- baclofen
- (+-)-Baclofen
- 4-amino-3-(4-chlorophenyl)butanoic acid
- 4-Amino-3-(4-chlorophenyl)butyric acid
- baclofene
- baclofeno
- baclofenum
- beta-(4-Chlorophenyl)gaba
- beta-(Aminomethyl)-4-chlorobenzenepropanoic acid
- beta-(Aminomethyl)-p-chlorohydrocinnamic acid
- beta-(p-Chlorophenyl)-gamma-aminobutyric acid
- DL-4-Amino-3-p-chlorophenylbutanoic acid
- DL-Baclofen
- gamma-Amino-beta-(p-chlorophenyl)butyric acid
Drug Classification
-
monocarboxylic acidView Class →
CHEBI:25384
-
monochlorobenzenesView Class →
CHEBI:83403
-
primary amino compoundView Class →
CHEBI:50994
-
gamma-amino acidView Class →
CHEBI:33707
-
t172268
-
t172403
-
t172698
-
t172798
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 1292
- oboInOwl#hasDbXref
- Wikipedia:Baclofen
- core#notation
- CHEBI:2972
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 1292
- oboInOwl#hasDbXref
- Wikipedia:Baclofen
- oboInOwl#id
- CHEBI:2972
- core#notation
- CHEBI:2972
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_51373
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- chebi#is_tautomer_of
- http://purl.obolibrary.org/obo/CHEBI_187893
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- has_treatment
- http://purl.obolibrary.org/obo/DOID_0110791
- owl#someValuesFrom
- t3839371
- owl#annotatedSource
- t173191