Discuss This Drug

Baclofen

CHEBI:CHEBI_2972

Definition

A monocarboxylic acid that is butanoic acid substituted by an amino group at position 4 and a 4-chlorophenyl group at position 3. It acts as a central nervous system depressant, GABA agonist and muscle relaxant.

Chemical Information

Molecular Formula
C10H12ClNO2
Molecular Mass
213.66100
Charge
0
SMILES
NCC(CC(O)=O)c1ccc(Cl)cc1
InChI
InChI=1S/C10H12ClNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14)
InChIKey
KPYSYYIEGFHWSV-UHFFFAOYSA-N

Alternative Names

  • baclofen
  • (+-)-Baclofen
  • 4-amino-3-(4-chlorophenyl)butanoic acid
  • 4-Amino-3-(4-chlorophenyl)butyric acid
  • baclofene
  • baclofeno
  • baclofenum
  • beta-(4-Chlorophenyl)gaba
  • beta-(Aminomethyl)-4-chlorobenzenepropanoic acid
  • beta-(Aminomethyl)-p-chlorohydrocinnamic acid
  • beta-(p-Chlorophenyl)-gamma-aminobutyric acid
  • DL-4-Amino-3-p-chlorophenylbutanoic acid
  • DL-Baclofen
  • gamma-Amino-beta-(p-chlorophenyl)butyric acid

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
1292
oboInOwl#hasDbXref
Wikipedia:Baclofen
core#notation
CHEBI:2972

Additional References

Wikipedia:Baclofen

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

dosage_form
GRANULE
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
application_number
ANDA210777
product_ndc
71335-9759
oboInOwl#hasOBONamespace
chebi_ontology
generic_name
Baclofen (Process-B)
brand_name
Gablofen
brand_name_base
Gablofen
DRON_00010000
1292
oboInOwl#hasDbXref
Wikipedia:Baclofen
oboInOwl#id
CHEBI:2972
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_51373
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#is_tautomer_of
http://purl.obolibrary.org/obo/CHEBI_187893
listing_expiration_date
20241231
marketing_start_date
20011024
labeler_name
Nexus Pharmaceuticals Inc
route
INTRATHECAL
package_ndc
71335-1796-1
spl_id
f2a55c02-e624-7ce6-e053-2a95a90a6155
package_description
90 TABLET in 1 BOTTLE (71335-1797-7)
package_marketing_start_date
24-OCT-01
rxcui
1666615
unii
H789N3FKE8
spl_set_id
7ed13ef7-329e-40cb-b9b1-31a4bf32ac98
manufacturer_name
DIRECT RX
active_ingredient_strength
2000 ug/mL
active_ingredient_name
BACLOFEN
nui
N0000175759
upc
0368134401163
core#notation
CHEBI:2972
pharm_class_epc
gamma-Aminobutyric Acid-ergic Agonist [EPC]
pharm_class
GABA B Agonists [MoA]
pharm_class_moa
GABA B Agonists [MoA]
brand_name_suffix
DS
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_0110791
owl#someValuesFrom
t3839371
owl#annotatedSource
t173191