Discuss This Drug

Benztropine

CHEBI:CHEBI_3048

Definition

Tropane in which a hydrogen at position 3 is substituted by a diphenylmethoxy group (endo-isomer). An acetylcholine receptor antagonist, it is used (particularly as its methanesulphonate salt) in the treatment of Parkinson's disease, and to reduce parkinsonism and akathisia side effects of antipsychotic treatments.

Chemical Information

Molecular Formula
C21H25NO
Molecular Mass
307.42930
Charge
0
SMILES
[H][C@]1(C[C@]2([H])CC[C@]([H])(C1)N2C)OC(c1ccccc1)c1ccccc1
InChI
InChI=1S/C21H25NO/c1-22-18-12-13-19(22)15-20(14-18)23-21(16-8-4-2-5-9-16)17-10-6-3-7-11-17/h2-11,18-21H,12-15H2,1H3/t18-,19+,20+
InChIKey
GIJXKZJWITVLHI-PMOLBWCYSA-N

Alternative Names

  • (3-endo)-3-(diphenylmethoxy)-8-methyl-8-azabicyclo[3.2.1]octane
  • 3alpha-(diphenylmethoxy)-1alphaH,5alphaH-tropane
  • 3alpha-(diphenylmethoxy)tropane
  • 3alpha-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane
  • 3endo-benzhydryloxytropane
  • benzatropina
  • benzatropine
  • Benzatropine
  • benzatropinum
  • benzhydryl 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ether
  • Benztropine
  • tropine benzohydryl ether

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:3048
DRON_00010000
1424
oboInOwl#hasDbXref
Wikipedia:Benzatropine

Additional References

Wikipedia:Benzatropine

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

listing_expiration_date
20241231
route
INTRAVENOUS
labeler_name
Curia Wisconsin, Inc.
marketing_start_date
19961212
spl_id
47702a3e-1173-4265-8583-d8e675b20ecd
package_ndc
0603-2434-32
application_number
ANDA090294
core#notation
CHEBI:3048
pharm_class
Cholinergic Antagonists [MoA]
active_ingredient_strength
.5 mg/1
upc
0368475512016
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
package_description
1000 TABLET in 1 BOTTLE, PLASTIC (0603-2434-32)
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
1424
oboInOwl#hasDbXref
Wikipedia:Benzatropine
generic_name
Benztropine mesylate
oboInOwl#id
CHEBI:3048
oboInOwl#hasAlternativeId
CHEBI:661238
product_type
BULK INGREDIENT
dosage_form
INJECTION
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
brand_name
BENZTROPINE MESYLATE
brand_name_base
BENZTROPINE MESYLATE
product_ndc
0603-2434
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50370
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
rxcui
885219
manufacturer_name
Navinta LLC
package_marketing_start_date
12-DEC-96
active_ingredient_name
BENZTROPINE MESYLATE
unii
WMJ8TL7510
spl_set_id
f82c6455-f36b-49d7-881e-6601d513d846
has_treatment
http://purl.obolibrary.org/obo/DOID_0060940
owl#annotatedSource
t173205
owl#someValuesFrom
t2999781