Discuss This Drug

acemetacin

CHEBI:CHEBI_31162

Definition

A carboxylic ester that is the carboxymethyl ester of indometacin. A non-steroidal anti-inflammatory drug, it is used in the treatment of rheumatoid arthritis, osteoarthritis, and low back pain, as well as for postoperative pain and inflammation. Its activity is due to both acemetacin and its major metabolite, indometacin.

Chemical Information

Molecular Formula
C21H18ClNO6
Molecular Mass
415.82400
Charge
0
SMILES
COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)OCC(O)=O)c2c1
InChI
InChI=1S/C21H18ClNO6/c1-12-16(10-20(26)29-11-19(24)25)17-9-15(28-2)7-8-18(17)23(12)21(27)13-3-5-14(22)6-4-13/h3-9H,10-11H2,1-2H3,(H,24,25)
InChIKey
FSQKKOOTNAMONP-UHFFFAOYSA-N

Alternative Names

  • {2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetoxy}acetic acid
  • acemetacin
  • acemetacina
  • acemetacine
  • acemetacinum
  • Acemix
  • Emflex
  • indometacin carboxymethyl ester
  • indometacin glycolic ester
  • indomethacin carboxymethyl ester
  • indomethacin glycolic ester
  • K 708
  • K-708
  • Rantudil
  • Solart
  • TV-1322
  • TVX 3322

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
16695
oboInOwl#hasDbXref
Wikipedia:Acemetacin
core#notation
CHEBI:31162

Additional References

Wikipedia:Acemetacin

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
16695
oboInOwl#hasDbXref
Wikipedia:Acemetacin
oboInOwl#id
CHEBI:31162
core#notation
CHEBI:31162
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_49662
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35544
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_108133
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect15872
owl#annotatedSource
t176709
owl#someValuesFrom
t3003758