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Alfacalcidol

CHEBI:CHEBI_31186

Definition

A member of the class of D3 vitamins that is calciol in which the hydrogen at the 1alpha position is replaced by a hydroxy group. It is an active metabolite of cholecalciferol, which performs important functions in regulation of the calcium balance and the bone metabolism.

Chemical Information

Molecular Formula
C27H44O2
Molecular Mass
400.63710
Charge
0
SMILES
CC(C)CCC[C@@H](C)[C@H]1CC[C@@H]2[C@]1(C)CCC\C2=C/C=C1/C[C@@H](O)C[C@H](O)C1=C
InChI
InChI=1S/C27H44O2/c1-18(2)8-6-9-19(3)24-13-14-25-21(10-7-15-27(24,25)5)11-12-22-16-23(28)17-26(29)20(22)4/h11-12,18-19,23-26,28-29H,4,6-10,13-17H2,1-3,5H3/b21-11+,22-12-/t19-,23-,24-,25+,26+,27-/m1/s1
InChIKey
OFHCOWSQAMBJIW-AVJTYSNKSA-N

Alternative Names

  • (1S,3R,5Z,7E)-9,10-secocholesta-5,7,10-triene-1,3-diol
  • (5Z,7E)-9,10-seco-5,7,10(19)-cholestatrien-1alpha,3beta-diol
  • 1alpha-hydroxy-vitamin D3
  • 1alpha-hydroxycholecalciferol
  • 1alpha-hydroxyvitamin D3
  • 9,10-secocholesta-5,7,10(19)-triene-1alpha,3beta-diol
  • alfacalcidol
  • alfacalcidol
  • alfacalcidolum
  • Alsiodol

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
12062
oboInOwl#hasDbXref
Reaxys:2064794
core#notation
CHEBI:31186

Additional References

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Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
12062
oboInOwl#hasDbXref
Reaxys:2064794
oboInOwl#id
CHEBI:31186
core#notation
CHEBI:31186
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50646
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_0080340
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_107176
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect15922
owl#annotatedSource
t176703
owl#someValuesFrom
t788854