emtricitabine
CHEBI:CHEBI_31536
Definition
An organofluorine compound that is 5-fluorocytosine substituted at the 1 position by a 2-(hydroxymethyl)-1,3-oxathiolan-5-yl group (2R,5S configuration). It is used in combination therapy for the treatment of HIV-1 infection.
Chemical Information
- Molecular Formula
- C8H10FN3O3S
- Molecular Mass
- 247.24700
- Charge
- 0
- SMILES
- Nc1nc(=O)n(cc1F)[C@@H]1CS[C@H](CO)O1
- InChI
- InChI=1S/C8H10FN3O3S/c9-4-1-12(8(14)11-7(4)10)5-3-16-6(2-13)15-5/h1,5-6,13H,2-3H2,(H2,10,11,14)/t5-,6+/m0/s1
- InChIKey
- XQSPYNMVSIKCOC-NTSWFWBYSA-N
Alternative Names
- (-)-(2R,5S)-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine
- (-)-2'-deoxy-5-fluoro-3'-thiacytidine
- (-)-beta-2',3'-dideoxy-5-fluoro-3'-thiacytidine
- (-)-cis-4-amino-5-fluoro-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one
- (-)-FTC
- (2R-cis)-4-amino-5-fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2(1H)-pyrimidinone
- 4-amino-5-fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one
- 4-Amino-5-fluoro-1-((2R,5S)-2-hydroxymethyl-[1,3]oxathiolan-5-yl)-1H-pyrimidin-2-one
- 4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one
- 5-fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine
- Emtricitabine
- EMTRICITABINE
Treatment Applications
Drug Classification
-
nucleoside analogueView Class →
CHEBI:60783
-
organofluorine compoundView Class →
CHEBI:37143
-
pyrimidoneView Class →
CHEBI:38337
-
monothioacetalView Class →
CHEBI:59793
-
t179460
-
t180205
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- oboInOwl#hasDbXref
- Wikipedia:Emtricitabine
- DRON_00010000
- 276237
- core#notation
- CHEBI:31536
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- oboInOwl#hasDbXref
- Wikipedia:Emtricitabine
- DRON_00010000
- 276237
- oboInOwl#hasAlternativeId
- CHEBI:174911
- oboInOwl#id
- CHEBI:31536
- core#notation
- CHEBI:31536
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_53756
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_113029
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect16935
- owl#annotatedSource
- t180307
- owl#someValuesFrom
- t3318285