Discuss This Drug

emtricitabine

CHEBI:CHEBI_31536

Definition

An organofluorine compound that is 5-fluorocytosine substituted at the 1 position by a 2-(hydroxymethyl)-1,3-oxathiolan-5-yl group (2R,5S configuration). It is used in combination therapy for the treatment of HIV-1 infection.

Chemical Information

Molecular Formula
C8H10FN3O3S
Molecular Mass
247.24700
Charge
0
SMILES
Nc1nc(=O)n(cc1F)[C@@H]1CS[C@H](CO)O1
InChI
InChI=1S/C8H10FN3O3S/c9-4-1-12(8(14)11-7(4)10)5-3-16-6(2-13)15-5/h1,5-6,13H,2-3H2,(H2,10,11,14)/t5-,6+/m0/s1
InChIKey
XQSPYNMVSIKCOC-NTSWFWBYSA-N

Alternative Names

  • (-)-(2R,5S)-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine
  • (-)-2'-deoxy-5-fluoro-3'-thiacytidine
  • (-)-beta-2',3'-dideoxy-5-fluoro-3'-thiacytidine
  • (-)-cis-4-amino-5-fluoro-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one
  • (-)-FTC
  • (2R-cis)-4-amino-5-fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2(1H)-pyrimidinone
  • 4-amino-5-fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one
  • 4-Amino-5-fluoro-1-((2R,5S)-2-hydroxymethyl-[1,3]oxathiolan-5-yl)-1H-pyrimidin-2-one
  • 4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one
  • 5-fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine
  • Emtricitabine
  • EMTRICITABINE

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Emtricitabine
DRON_00010000
276237
core#notation
CHEBI:31536

Additional References

Wikipedia:Emtricitabine

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Emtricitabine
DRON_00010000
276237
oboInOwl#hasAlternativeId
CHEBI:174911
oboInOwl#id
CHEBI:31536
generic_name
emtricitabine and tenofovir alafenamide
brand_name
DESCOVY
brand_name_base
DESCOVY
product_ndc
70710-1365
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_53756
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
listing_expiration_date
20241231
marketing_start_date
20071023
spl_id
6cf3d607-b4fa-473d-a9bb-01a9a94a6d8d
labeler_name
Aurobindo Pharma Limited
manufacturer_name
Cipla USA Inc.
package_marketing_start_date
07-JUN-13
package_description
9912 TABLET, FILM COATED in 1 CONTAINER (66406-0102-0)
active_ingredient_name
TENOFOVIR ALAFENAMIDE FUMARATE
rxcui
2590643
active_ingredient_strength
133 mg/1
unii
FWF6Q91TZO
spl_set_id
d21888d6-d5a8-49fe-9e07-e854cf78b712
nui
N0000009947
upc
0303781930932
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
dosage_form
SOLUTION
application_number
ANDA206436
package_ndc
50090-6494-1
core#notation
CHEBI:31536
pharm_class_epc
Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor [EPC]
pharm_class
Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor [EPC]
pharm_class_moa
Nucleoside Reverse Transcriptase Inhibitors [MoA]
pharm_class_cs
Nucleosides [CS]
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
route
ORAL
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_113029
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect16935
owl#annotatedSource
t180307
owl#someValuesFrom
t3318285