Discuss This Drug

fulvestrant

CHEBI:CHEBI_31638

Definition

A 3-hydroxy steroid that is 17beta-estradiol in which the 7alpha hydrogen has been replaced by a nonyl group in which one of the hydrogens of the terminal methyl has been replaced by a (4,4,5,5,5-pentafluoropentyl)sulfinyl group. An estrogen receptor antagonist, it is used in the treatment of breast cancer.

Chemical Information

Molecular Formula
C32H47F5O3S
Molecular Mass
606.773
Charge
0
SMILES
C=1C=C(C=C2C1[C@]3(CC[C@@]4([C@H](CC[C@]4([C@@]3([C@@H](C2)CCCCCCCCCS(=O)CCCC(C(F)(F)F)(F)F)[H])[H])O)C)[H])O
InChI
InChI=1S/C32H47F5O3S/c1-30-17-15-26-25-12-11-24(38)21-23(25)20-22(29(26)27(30)13-14-28(30)39)10-7-5-3-2-4-6-8-18-41(40)19-9-16-31(33,34)32(35,36)37/h11-12,21-22,26-29,38-39H,2-10,13-20H2,1H3/t22-,26-,27+,28+,29-,30+,41?/m1/s1
InChIKey
VWUXBMIQPBEWFH-WCCTWKNTSA-N

Alternative Names

  • (7alpha,17beta)-7-{9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl}estra-1(10),2,4-triene-3,17-diol
  • 7alpha-{9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl}estra-1(10),2,4-triene-3,17beta-diol
  • Faslodex
  • fulvestrant
  • fulvestrantum
  • ICI 182780
  • ICI-182780

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
282357
oboInOwl#hasDbXref
Wikipedia:Fulvestrant
core#notation
CHEBI:31638

Additional References

Wikipedia:Fulvestrant

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

listing_expiration_date
20241231
route
INTRAVENOUS
marketing_start_date
20150618
spl_id
99e95543-2f0d-4992-80ff-00a4f92d6e06
package_ndc
0781-3532-12
labeler_name
Fresenius Kabi USA, LLC
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
282357
oboInOwl#hasDbXref
Wikipedia:Fulvestrant
oboInOwl#id
CHEBI:31638
oboInOwl#hasAlternativeId
CHEBI:87729
generic_name
FULVESTRANT
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
dosage_form
INJECTION, SOLUTION
brand_name
FASLODEX
brand_name_base
FASLODEX
product_ndc
0781-3532
application_number
NDA021344
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50837
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_parent_hydride
http://purl.obolibrary.org/obo/CHEBI_23966
manufacturer_name
Northstar Rx, LLC,
package_marketing_start_date
29-JUL-20
package_description
2 SYRINGE, GLASS in 1 CARTON (0781-3532-12) / 5 mL in 1 SYRINGE, GLASS (0781-3532-01)
core#notation
CHEBI:31638
rxcui
727954
active_ingredient_strength
25000 g/25000g
active_ingredient_name
FULVESTRANT
unii
22X328QOC4
spl_set_id
141f439e-078c-4a59-acff-ebf7685f55b8
nui
N0000000168
pharm_class_epc
Estrogen Receptor Antagonist [EPC]
pharm_class
Selective Estrogen Receptor Modulators [MoA]
pharm_class_moa
Selective Estrogen Receptor Modulators [MoA]
upc
0368001522861
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_112973
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect17256
has_treatment
http://purl.obolibrary.org/obo/DOID_0060076
owl#annotatedSource
t180187
owl#someValuesFrom
t631268