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bretylium

CHEBI:CHEBI_3172

Definition

A quaternary ammonium cation having 2-bromobenzyl, ethyl and two methyl groups attached to the nitrogen. It blocks noradrenaline release from the peripheral sympathetic nervous system, and is used in emergency medicine, cardiology, and other specialties for the acute management of ventricular tachycardia and ventricular fibrillation.

Chemical Information

Molecular Formula
C11H17BrN
Molecular Mass
243.16300
Charge
+1
SMILES
CC[N+](C)(C)Cc1ccccc1Br
InChI
InChI=1S/C11H17BrN/c1-4-13(2,3)9-10-7-5-6-8-11(10)12/h5-8H,4,9H2,1-3H3/q+1
InChIKey
AAQOQKQBGPPFNS-UHFFFAOYSA-N

Alternative Names

  • (2-bromobenzyl)ethyldimethylaminium
  • 2-bromo-N-ethyl-N,N-dimethylbenzenemethanaminium
  • N-(2-bromobenzyl)-N,N-dimethylethanaminium
  • N-ethyl-N,N-dimethyl-2-bromobenzenemethanaminium

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
19685
oboInOwl#hasDbXref
Wikipedia:Bretylium
core#notation
CHEBI:3172

Additional References

Wikipedia:Bretylium

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
19685
oboInOwl#hasDbXref
Wikipedia:Bretylium
oboInOwl#id
CHEBI:3172
core#notation
CHEBI:3172
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_37887
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_109073
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect17380
owl#annotatedSource
t179875
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t3444954