Discuss This Drug

nateglinide

CHEBI:CHEBI_31897

Definition

An N-acyl-D-phenylalanine resulting from the formal condensation of the amino group of D-phenylalanine with the carboxy group of trans-4-isopropylcyclohexanecarboxylic acid. An orally-administered, rapidly-absorbed, short-acting insulinotropic agent, it is used for the treatment of type 2 diabetes mellitus.

Chemical Information

Molecular Formula
C19H27NO3
Molecular Mass
317.42260
Charge
0
SMILES
CC(C)[C@H]1CC[C@@H](CC1)C(=O)N[C@H](Cc1ccccc1)C(O)=O
InChI
InChI=1S/C19H27NO3/c1-13(2)15-8-10-16(11-9-15)18(21)20-17(19(22)23)12-14-6-4-3-5-7-14/h3-7,13,15-17H,8-12H2,1-2H3,(H,20,21)(H,22,23)/t15-,16-,17-/m1/s1
InChIKey
OELFLUMRDSZNSF-BRWVUGGUSA-N

Alternative Names

  • (-)-N-(trans-4-isopropylcyclohexanecarbonyl)-D-phenylalanine
  • A 4166
  • A-4166
  • AY 4166
  • AY-4166
  • AY4166
  • Fastic
  • N-[(trans-4-isopropylcyclohexyl)carbonyl]-D-phenylalanine
  • nateglinida
  • nateglinide
  • nateglinidum
  • Starlix
  • Starsis
  • trans-N-{[4-(1-methylethyl)cyclohexyl]carbonyl}-D-phenylalanine

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:31897
DRON_00010000
274332
oboInOwl#hasDbXref
Wikipedia:Nateglinide

Additional References

Wikipedia:Nateglinide

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:31897
pharm_class_moa
Potassium Channel Antagonists [MoA]
pharm_class
Glinide [EPC]
nui
N0000175448
pharm_class_epc
Glinide [EPC]
upc
0368382722164
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
listing_expiration_date
20241231
route
ORAL
marketing_start_date
20041122
labeler_name
Zydus Pharmaceuticals USA Inc.
spl_id
cc8dcb65-71ff-43f2-838f-347f4140f259
package_ndc
72241-003-05
application_number
ANDA077462
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
274332
oboInOwl#hasDbXref
Wikipedia:Nateglinide
oboInOwl#id
CHEBI:31897
generic_name
Nateglinide Micronised
product_type
BULK INGREDIENT
dosage_form
TABLET, COATED
marketing_category
BULK INGREDIENT
brand_name
NATEGLINIDE
brand_name_base
NATEGLINIDE
product_ndc
72241-003
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_68612
rxcui
314142
package_marketing_start_date
22-NOV-04
manufacturer_name
Zydus Pharmaceuticals USA Inc.
active_ingredient_strength
25 kg/25kg
active_ingredient_name
NATEGLINIDE
package_description
100 TABLET, COATED in 1 BOTTLE (72241-003-05)
unii
41X3PWK4O2
spl_set_id
b41f4180-96a7-411d-b827-5021e534f556
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect17775
owl#annotatedSource
t183858
owl#someValuesFrom
t920678