Discuss This Drug

pirfenidone

CHEBI:CHEBI_32016

Definition

A pyridone that is 2-pyridone substituted at positions 1 and 5 by phenyl and methyl groups respectively. An anti-inflammatory drug used for the treatment of idiopathic pulmonary fibrosis.

Chemical Information

Molecular Formula
C12H11NO
Molecular Mass
185.22180
Charge
0
SMILES
Cc1ccc(=O)n(c1)-c1ccccc1
InChI
InChI=1S/C12H11NO/c1-10-7-8-12(14)13(9-10)11-5-3-2-4-6-11/h2-9H,1H3
InChIKey
ISWRGOKTTBVCFA-UHFFFAOYSA-N

Alternative Names

  • 5-methyl-1-phenylpyridin-2(1H)-one
  • AMR 69
  • AMR-69
  • Esbriet
  • pirfenidona
  • pirfenidone
  • pirfenidonum

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
1592254
oboInOwl#hasDbXref
Wikipedia:Pirfenidone
core#notation
CHEBI:32016

Additional References

Wikipedia:Pirfenidone

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
1592254
oboInOwl#hasDbXref
Wikipedia:Pirfenidone
oboInOwl#id
CHEBI:32016
generic_name
PIRFENIDONE
brand_name
ESBRIET
brand_name_base
ESBRIET
product_ndc
0781-8086
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35481
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
listing_expiration_date
20241231
route
ORAL
marketing_start_date
20220511
spl_id
b22f432a-14bf-44b2-bb86-63dc277ce7ed
package_ndc
0781-8086-92
package_description
90 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (0781-8086-92)
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
dosage_form
TABLET, COATED
labeler_name
TYCHE INDUSTRIES LIMITED
application_number
ANDA212560
manufacturer_name
MSN LABORATORIES PRIVATE LIMITED
package_marketing_start_date
16-OCT-14
core#notation
CHEBI:32016
rxcui
1868020
active_ingredient_strength
801 mg/1
active_ingredient_name
PIRFENIDONE
unii
D7NLD2JX7U
spl_set_id
7f5f7cc9-394e-4da0-87eb-84cfff9707a3
nui
M0018236
pharm_class_epc
Pyridone [EPC]
pharm_class
Pyridones [CS]
pharm_class_cs
Pyridones [CS]
upc
0372603258011
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_5139
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https://w3id.org/def/predibionto#has_drug_113226
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https://w3id.org/def/predibionto#has_side_effect18308
owl#annotatedSource
t183846
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t3103316