Discuss This Drug

pitavastatin

CHEBI:CHEBI_32020

Definition

A dihydroxy monocarboxylic acid that is (6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]hept-6-enoic acid in which the two hydroxy groups are located at positions 3 and 5 (the 3R,5S-stereoisomer). Used as its calcium salt for treatment of hypercholesterolemia (elevated levels of cholesterol in the blood) on patients unable to sufficiently lower their cholesterol levels by diet and exercise.

Chemical Information

Molecular Formula
C25H24FNO4
Molecular Mass
421.46080
Charge
0
SMILES
O[C@H](C[C@H](O)\C=C\c1c(nc2ccccc2c1-c1ccc(F)cc1)C1CC1)CC(O)=O
InChI
InChI=1S/C25H24FNO4/c26-17-9-7-15(8-10-17)24-20-3-1-2-4-22(20)27-25(16-5-6-16)21(24)12-11-18(28)13-19(29)14-23(30)31/h1-4,7-12,16,18-19,28-29H,5-6,13-14H2,(H,30,31)/b12-11+/t18-,19-/m1/s1
InChIKey
VGYFMXBACGZSIL-MCBHFWOFSA-N

Alternative Names

  • (3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoic acid
  • NK 104
  • NK-104
  • pitavastatia
  • pitavastatin
  • pitavastatine
  • pitavastatinum

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
861634
oboInOwl#hasDbXref
Wikipedia:Pitavastatin
core#notation
CHEBI:32020

Additional References

Wikipedia:Pitavastatin

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

package_description
1 BAG in 1 DRUM (17337-0311-1) / 1 BAG in 1 BAG / 2.5 kg in 1 BAG
package_ndc
70771-1118-7
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
listing_expiration_date
20241231
route
ORAL
dosage_form
GRANULE
labeler_name
Kowa Pharmaceuticals America, Inc.
application_number
ANDA205961
marketing_start_date
20150220
spl_id
5fac90c8-b58d-1395-e053-2991aa0a6de7
product_ndc
0378-5057
rxcui
2689127
manufacturer_name
Kowa Pharmaceuticals America, Inc.
package_marketing_start_date
20-FEB-15
unii
M5681Q5F9P
spl_set_id
7fbfcc0c-9251-456d-a525-e62cfd8abd4b
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
861634
oboInOwl#hasDbXref
Wikipedia:Pitavastatin
oboInOwl#id
CHEBI:32020
generic_name
Pitavastatin Calcium
brand_name
NIKITA
brand_name_base
NIKITA
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_22586
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_71260
core#notation
CHEBI:32020
active_ingredient_strength
4.18 mg/1
nui
N0000000121
pharm_class_epc
HMG-CoA Reductase Inhibitor [EPC]
pharm_class
Hydroxymethylglutaryl-CoA Reductase Inhibitors [MoA]
pharm_class_moa
Hydroxymethylglutaryl-CoA Reductase Inhibitors [MoA]
active_ingredient_name
PITAVASTATIN
upc
0365162029093
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect18325
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_71260
owl#annotatedSource
t183835
owl#someValuesFrom
t1025081