Discuss This Drug

Proglumide

CHEBI:CHEBI_32058

Definition

A racemate composed of equal amounts of (R)- and (S)-proglumide. A non-selective CCK antagonist that was used primarily for treatment of stomach ulcers, but has been replaced by newer drugs.

Chemical Information

Molecular Formula
C18H26N2O4
Molecular Mass
334.41000
Charge
0
SMILES
CCCN(CCC)C(=O)C(CCC(O)=O)NC(=O)c1ccccc1
InChI
InChI=1S/C18H26N2O4/c1-3-12-20(13-4-2)18(24)15(10-11-16(21)22)19-17(23)14-8-6-5-7-9-14/h5-9,15H,3-4,10-13H2,1-2H3,(H,19,23)(H,21,22)
InChIKey
DGMKFQYCZXERLX-UHFFFAOYSA-N

Alternative Names

  • (+-)-4-benzamido-N,N-dipropylglutaramic acid
  • (+-)-proglumide
  • (RS)-proglumide
  • DL-proglumide
  • proglumida
  • proglumide
  • proglumidum
  • rac-N(2)-benzoyl-N,N-dipropyl-alpha-glutamine
  • racemic proglumide

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
8730
oboInOwl#hasDbXref
Wikipedia:Proglumide
core#notation
CHEBI:32058

Additional References

Wikipedia:Proglumide

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
8730
oboInOwl#hasDbXref
Wikipedia:Proglumide
oboInOwl#id
CHEBI:32058
core#notation
CHEBI:32058
generic_name
Proglumide
listing_expiration_date
20241231
dosage_form
POWDER
marketing_start_date
20210622
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
active_ingredient_strength
100 kg/100kg
package_marketing_start_date
22-JUN-21
product_ndc
51604-1092
labeler_name
COSMA SpA
spl_id
c56f9ddd-fa40-5715-e053-2995a90a8d1d
active_ingredient_name
PROGLUMIDE
package_ndc
51604-1092-0
package_description
50 kg in 1 DRUM (51604-1092-0)
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_73296
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
BFO_0000051
http://purl.obolibrary.org/obo/CHEBI_76268
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http://www.w3.org/2002/07/owl#Class
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http://purl.obolibrary.org/obo/CHEBI_76263
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t183804
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t897209