Bumetanide
CHEBI:CHEBI_3213
Definition
A member of the class of benzoic acids that is 4-phenoxybenzoic acid in which the hydrogens ortho to the phenoxy group are substituted by butylamino and sulfamoyl groups. Bumetanide is a diuretic, and is used for treatment of oedema associated with congestive heart failure, hepatic and renal disease.
Chemical Information
- Molecular Formula
- C17H20N2O5S
- Molecular Mass
- 364.41600
- Charge
- 0
- SMILES
- CCCCNc1cc(cc(c1Oc1ccccc1)S(N)(=O)=O)C(O)=O
- InChI
- InChI=1S/C17H20N2O5S/c1-2-3-9-19-14-10-12(17(20)21)11-15(25(18,22)23)16(14)24-13-7-5-4-6-8-13/h4-8,10-11,19H,2-3,9H2,1H3,(H,20,21)(H2,18,22,23)
- InChIKey
- MAEIEVLCKWDQJH-UHFFFAOYSA-N
Alternative Names
- 3-(aminosulfonyl)-5-(butylamino)-4-phenoxybenzoic acid
- 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid
- 3-butylamino-4-(phenoxy)-5-sulfamoylbenzoic acid
- 3-butylamino-4-phenoxy-5-sulfamoyl-benzoic acid
- 3-butylamino-4-phenoxy-5-sulfamoylbenzoic acid
- bumetanida
- bumetanide
- bumetanidum
Drug Classification
-
sulfonamideView Class →
CHEBI:35358
-
benzoic acidsView Class →
CHEBI:22723
-
amino acidView Class →
CHEBI:33709
-
Amino AcidsView Class →
CHEBI:33709
-
t182859
-
t183420
-
t183464
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- core#notation
- CHEBI:3213
- oboInOwl#hasDbXref
- Wikipedia:Bumetanide
- DRON_00010000
- 1808
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- package_description
- 80000 TABLET in 1 CONTAINER (60468-001-01)
- package_ndc
- 72162-2196-1
- package_marketing_start_date
- 19830228
- listing_expiration_date
- 20241231
- route
- INTRAVENOUS
- spl_id
- 7ceb4759-e548-2757-e053-2a91aa0aebf1
- marketing_start_date
- 20150810
- rxcui
- 1727569
- manufacturer_name
- Rising Pharma Holdings, Inc
- unii
- 0Y2S3XUQ5H
- spl_set_id
- 9bd4fcd3-3020-41f2-b112-023b5db4487d
- core#notation
- CHEBI:3213
- active_ingredient_strength
- 2 kg/2kg
- nui
- N0000175590
- pharm_class_epc
- Loop Diuretic [EPC]
- pharm_class
- Increased Diuresis at Loop of Henle [PE]
- pharm_class_pe
- Increased Diuresis at Loop of Henle [PE]
- active_ingredient_name
- BUMETANIDE
- upc
- 0342799121017
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
- dosage_form
- INJECTION, SOLUTION
- labeler_name
- Rising Pharma Holdings, Inc
- application_number
- ANDA215364
- product_ndc
- 43353-288
- oboInOwl#hasOBONamespace
- chebi_ontology
- oboInOwl#hasDbXref
- Wikipedia:Bumetanide
- DRON_00010000
- 1808
- generic_name
- BUMETANIDE
- brand_name
- Bumex
- brand_name_base
- Bumex
- oboInOwl#hasAlternativeId
- CHEBI:239281
- oboInOwl#id
- CHEBI:3213
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_131770
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- BFO_0000053
- http://purl.obolibrary.org/obo/DRON_00020327
- has_treatment
- http://purl.obolibrary.org/obo/DOID_0080436
- owl#annotatedSource
- t183853
- owl#someValuesFrom
- t3004126