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Tacalcitol

CHEBI:CHEBI_32176

Definition

A hydroxy seco-steroid that is calciol which carries hydroxy groups at positions 1S and 24R. It is a vitamin D3 analog which is used for the treatment of psoriasis vulgaris in adults, especially on the scalp.

Chemical Information

Molecular Formula
C27H44O3
Molecular Mass
416.646
Charge
0
SMILES
[H][C@@]1(CC[C@@]2([H])\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C)[C@H](C)CC[C@@H](O)C(C)C
InChI
InChI=1S/C27H44O3/c1-17(2)25(29)13-8-18(3)23-11-12-24-20(7-6-14-27(23,24)5)9-10-21-15-22(28)16-26(30)19(21)4/h9-10,17-18,22-26,28-30H,4,6-8,11-16H2,1-3,5H3/b20-9+,21-10-/t18-,22-,23-,24+,25-,26+,27-/m1/s1
InChIKey
BJYLYJCXYAMOFT-RSFVBTMBSA-N

Alternative Names

  • (1alpha,24R)-1,24-dihydroxyvitamin D3
  • (1S,3R,5Z,7E,24R)-9,10-secocholesta-5,7,10-triene-1,3,24-triol
  • 1-alpha,24(R)-dihydroxyvitamin D3
  • Bonalfa
  • PRI 2191
  • PRI-2191
  • tacalcitol
  • tacalcitolum
  • TV 02
  • TV-02

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
291204
oboInOwl#hasDbXref
Wikipedia:Tacalcitol
core#notation
CHEBI:32176

Additional References

Wikipedia:Tacalcitol

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

rdf-schema#range
https://w3id.org/def/predibionto#has_drug_109352
has_treatment
http://purl.obolibrary.org/obo/DOID_6498
owl#annotatedSource
t183867
owl#someValuesFrom
t568613
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
291204
oboInOwl#hasDbXref
Wikipedia:Tacalcitol
oboInOwl#id
CHEBI:32176
core#notation
CHEBI:32176
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50748
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_28940
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class