tazarotene

CHEBI:CHEBI_32184

Definition

The ethyl ester of tazarotenic acid. A prodrug for tazarotenic acid, it is used for the treatment of psoriasis, acne, and sun-damaged skin.

Chemical Information

Molecular Formula
C21H21NO2S
Molecular Mass
351.46200
Charge
0
SMILES
CCOC(=O)c1ccc(nc1)C#Cc1ccc2SCCC(C)(C)c2c1
InChI
InChI=1S/C21H21NO2S/c1-4-24-20(23)16-7-9-17(22-14-16)8-5-15-6-10-19-18(13-15)21(2,3)11-12-25-19/h6-7,9-10,13-14H,4,11-12H2,1-3H3
InChIKey
OGQICQVSFDPSEI-UHFFFAOYSA-N

Alternative Names

  • Avage
  • ethyl 6-[(4,4-dimethyl-3,4-dihydro-2H-thiochromen-6-yl)ethynyl]nicotinate
  • tazarotene
  • tazaroteno
  • tazarotenum
  • Tazorac
  • Zorac

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
83947
oboInOwl#hasDbXref
Wikipedia:Tazarotene
core#notation
CHEBI:32184

Additional References

Wikipedia:Tazarotene

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
83947
oboInOwl#hasDbXref
Wikipedia:Tazarotene
oboInOwl#id
CHEBI:32184
generic_name
TAZAROTENE
brand_name
FABIOR
brand_name_base
FABIOR
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
dosage_form
AEROSOL, FOAM
application_number
ANDA215433
product_ndc
55679-114
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50266
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_73129
labeler_name
CHONGQING HUAPONT SHENGCHEM PHARM. CO., LTD.
listing_expiration_date
20241231
route
CUTANEOUS
marketing_start_date
20080314
spl_id
3986fc19-9aa2-4ed3-867e-aa0df1b6c2a8
package_ndc
55679-114-02
core#notation
CHEBI:32184
rxcui
1293456
nui
M0018962
pharm_class_epc
Retinoid [EPC]
pharm_class
Retinoids [CS]
pharm_class_cs
Retinoids [CS]
active_ingredient_strength
.45 mg/g
active_ingredient_name
TAZAROTENE
unii
81BDR9Y8PS
spl_set_id
ecd718fd-c06e-4b3a-8aca-fa51e7c51a66
upc
0316110916309
brand_name_suffix
Plaque Psoriasis and Acne
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
manufacturer_name
ALMIRALL, LLC
package_marketing_start_date
01-APR-96
package_description
1 BAG in 1 DRUM (55679-114-02) / 6 kg in 1 BAG
has_treatment
http://purl.obolibrary.org/obo/DOID_9212
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_111153
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect19108
owl#annotatedSource
t183538
owl#someValuesFrom
t3472796